A CROSS-SECTIONAL STUDY IN PATIENTS WITH PRE-DIALYSIS CHRONIC KIDNEY DISEASE: QUALITY OF LIFE AND RELATED FACTORS

PREDİYALİZ KRONİK BÖBREK HASTALARINDA KESİTSEL BİR ÇALIŞMA: YAŞAM KALİTESİ VE ETKİLEYEN FAKTÖRLER

Abstract

OBJECTIVE: The incidence and prevalence of patients with chronic kidney disease (CKD) is increasing worldwide. It is often associated with a high prevalence of complications and worse quality of life. The main objective of this study is to evaluate quality of life (QOL) using the generic instrument short form-36 (SF-36) in patients with CKD and identify the possible influence of the degree of renal function, age, gender, education level, socioeconomic status, hemoglobin, albumin, HbA1c and 25 hydroxy vitamin D level on QOL. MATERIALS AND METHODS: For this cross-sectional study, we included 211 CKD patients ( median age 56 ± 13 years) admitted to the outpatient clinic of Antalya Research and Training Hospital Nephrology Unit between January and June 2016. Participants completed the short form-36 health survey (SF-36). Laboratory tests and clinical and demographic data were obtained. RESULTS: The patients were classified into CKD stages according to the CKD-EPI equation: 59,2% were in CKD Stage 1-3 and 40,8% were in Stage 4-5. The patients in Stage 4-5 had lower scores in physical aspects. Age influence QOL negatively. CKD patients with higher hemoglobin, albumin and 25 hydroxy vitamin D levels has better functional capacity and physical aspects. High HbA1c levels significantly associated with bad functional capacity. Education level and socioeconomic status is associated with QOL. CONCLUSIONS: Renal function, age, gender, education level and socioeconomic status influenced QOL. To imrove QOL in CKD patients we need to focus on factors that can be changed, such as improving the hemoglobin, albumin, HbA1c and 25 hydroxy vitamin D levels.

Özet

AMAÇ: Kronik Böbrek Hastalığı (KBH) insidansı ve prevalansı tüm dünyada artmaktadır. KBH’da sıklıkla komplikasyonlar fazladır ve kötü yaşam kalitesi ile birliktedir. Bu çalışmanın amacı Kısa form-36 (SF-36) ölçeği ile KBH’da yaşam kalitesinin değerlendirilmesi ve böbrek fonksiyonları, yaş, cinsiyet, eğitim düzeyi, sosyo ekonomik durum, hemoglobin, albumin, HBA1c, 25OHvitamin D düzeyinin yaşam kalitesi üzerindeki etkisinin araştırılmasıdır.