Journals / Turkish Journal of Chemistry / 2007 / Cilt: 31 - Sayı: 6
Fused Heterocycles: Synthesis of Some New Imidazopyridines as Anti-Mycobacterial Agents
- Journal
- Turkish Journal of Chemistry
- Pages
- 617–622
- DOI
- —
Abstract
The reaction of semicarbazones bearing an imidazo[1,2-a]pyridine ring system with mercaptoacetic acid was investigated. The anti-mycobacterial activity of the compounds thus obtained were evaluated against Mycobacterium tuberculosis H37Rv, using rifampin as the standard. Only IVe showed activity at 6.25 m g mL-1.
Özet
The reaction of semicarbazones bearing an imidazo[1,2-a]pyridine ring system with mercaptoacetic acid was investigated. The anti-mycobacterial activity of the compounds thus obtained were evaluated against Mycobacterium tuberculosis H37Rv, using rifampin as the standard. Only IVe showed activity at 6.25 m g mL-1.