Journals / Turkish Journal of Chemistry / 2008 / Cilt: 32 - Sayı: 6

Synthesis and Biological Activity of Allosteric Modulators of GABAB Receptors. Part 4. Synthesis of Potentially Fluorescent Acridines and Conformationally Restricted N-(arylpropyl)-1-arylethylamines

Pages
755–763
DOI
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Abstract

A series of 8 new derivatives of fendiline was prepared for evaluation as allosteric modulators of GABAB receptors: 4 based on acridine and 4 with restricted distance between the 2 aryl moieties.

Özet

A series of 8 new derivatives of fendiline was prepared for evaluation as allosteric modulators of GABAB receptors: 4 based on acridine and 4 with restricted distance between the 2 aryl moieties.

Keywords: Fendiline analogues, acridines, acridones, aminotetralins, aminoindanes, GABA.