Fetomaternal Effects of TSH Values in the Initial Stage of Pregnancy

Özet

Introduction: To examine the fetomaternal effects of TSH values considered to be high (≥2.5 and 0.3 and <4 μIU/mL in the first trimester of their pregnancy who were followed up in our clinic until giving birth were included to the study. Patient files were reviewed retrospectively. The 518 patients meeting the criteria were divided into 2 groups according to their initial TSH values; Group 1 consisted of patients with TSH <2.5 μIU/mL (n=410), and Group 2 of patients with TSH ≥2.5 and <4 μIU/mL (n=108). Demographic char- acteristics and poor pregnancy outcomes (PPO) of the patients were compared. Results: Comparing the demographic characteristics of the two groups formed according to the patients’ TSH values at the onset of their pregnancy, no statistically significant differences were found (p<0.05). When the two groups were compared in terms of poor pregnancy outcomes (PPO), no statistically significant difference was found either (p=.852; OR: 1.067; CI: 0.541-2.102). Discussion and Conclusion: In cases of subclinical hypothyroidism during pregnancy, refraining from medication does not cause PPO.