Factors Affecting the Development of Cardiovascular Events Among Patients with End-Stage Renal Disease Undergoing Hemodialysis in Sudan

Abstract

Purpose: This study aimed to determine factors that affected the development of new onset cardiovascular events among patients with end-stage renal disease ESRD undergoing hemodialysis HD at the Khartoum HD centers in Sudan.Methods: A prospective observational study was conducted among anemic ESRDpatients undergoing HD at Khartoum State HD centers. A total of 1015 patients undergoing HD were recruited from 12 HD centers. A standardized data collection form was used for collecting the required data. Logistic regression analysis was performed.Results: Of 1015 recruited patients, 534 52.6% were included in the final analysis; the 481 patients who were excluded comprised 194 19.1% patients who were transferred to other centers, 165 16.3% who died, 84 8.3% who were lost during follow-up, and 38 3.7% who underwent renal transplantation. The significant factors that affected the development of new cardiovascular events in 154 28.8% anemic ESRD patients were advanced age [for patients aged 45-64 years: odds ratio OR , 1.94; 95% confidence interval CI , 1.18-3.18; p=0.009 and for patients aged ≥65 years: OR, 10.88; 95% CI, 6.12-19.33; p