Assessment of the Electrocardiogram T-Wave Intervals with Acute Biliary Pancreatitis

Özet

Introduction: Cardiovascular involvement is one of the multisystemic manifestations of acute biliary pancreatitis. In this study, we aimed to examine, to our knowledge, for the first time, how the Tpeak-Tend (TpTe) interval, a highly predictive electrocardiographic marker, is affected in patients with acute biliary pancreatitis.Methods: A total of 68 subjects were recruited in this retrospective case-control study. To determine the Corrected QT Inter-vals (QTc) and TpTe intervals, the electrocardiographs of all subjects were manually examined using the precordial V5 lead.Results: We found that the TpTe and QTc intervals were longer in the cases compared to the controls, and this difference was statistically significant (p<0.05). With respect to acute biliary pancreatitis, the QTc had 68.4% sensitivity and 67% specificity (AUC=0.660, CI: 0.529-0.791; p=0.024) and the TpTe interval had 76.3% sensitivity and 63.3% specificity (AUC=0.647, CI: 0.508-0.787; p=0.038).Discussion and Conclusion: The Tpeak-Tend interval was evaluated for the risk of arrhythmia in patients with acute biliary pancreatitis. Our study demonstrated how the Tpeak-Tend and OTc intervals were affected in patients with acute biliary pancreatitis and that acute pancreatitis might be one of the causes of prolonged QTc and Tpeak-Tend intervals.