THE EFFECT OF NEUTROPHIL TO LYMPHOCYTE RATIO ON POSTOPERATIVE EARLY MORTALITY AND MORBIDITY IN HIP FRACTURE INTENSIVE CARE PATIENTS

YOĞUN BAKIM KALÇA KIRIĞI HASTALARINDA NÖTROFİL LENFOSİT ORANININ POSTOPERATİF ERKEN DÖNEM MORTALİTE VE MORBİDİTEYE ETKİSİ

Abstract

Objective: In this study the relation between the neutrophil and lymphocyte ratio (NLR) and mortality in patients with hip fracture accepted in ICU in the postoperative period was investigated. Method: The patients who were operated for hip fractures and accepted to ICU postoperatively between Jan 2015-Jun 2016 were included in the study. In Group Y (n=184) the patients who were survived and in Group K (n=15) the patients who did not survive were analysed retrospectively. Age, sex, coronary artery disease, general or regioal anesthesia technique for the surgery, NLR counts preoperatively and in the first postoperative day in the ICU and exitus at the early period were obtained. Results: One-hundred and ninety nine patients were included in the study. The demographic variables were similar between groups. There was no significant difference between preoperative and postoperative mean NLR between groups. The correlation between NLRpr/NLRpo and mortality was similar in Group Y and in Group K. Conclusion: In this study a correlation between NLR and morbidity and mortality of the patients with hip fracture was not demonstrated.

Özet

Amaç: Bu çal›flmada anestezi yo¤un bak›m›n›na postoperatif dönemde kabul edilen kalça k›r›¤› (KK) hastalar›nda nötrofil lenfosit oran› (NLO)’nun mortalite ve morbidite üzerine etkisi de¤erlendirildi. Yöntem: Ocak 2015-Haziran 2016 tarihleri aras›nda, kalça k›r›¤› (KK) nedeniyle opere olan ve yo¤un bak›ma kabul edilen hastalar çal›flmaya dahil edildi. Grup Y (n=184)’de yaflayan hastalar, Grup K ( n=15)’da eksitus kabul edilen hastalar retrospektif olarak de¤erlendirildi. Çal›flmaya dahil edilen hastalarda; yafl, cinsiyet, koroner arter hastal›¤› varl›¤›, genel veya spinal anestezi alt›nda opere edilmifl olmalar›, preoperatif dönem ve postoperatif 1. gün nötrofil ve lenfosit say›lar› ve oranlar› (NLO1 ve NLO2) ile erken dönemde eksitus olanlar kay›t edildi. Bulgular: Çal›flmam›za 199 hasta dahil edildi. Gruplar aras›nda demografik veriler benzerdi. Preoperatif ve postoperatif ortalama NLR de¤erleri aç›s›ndan Grup Y ve Grup K aras›nda fark yoktu. NLO1 ve NLO2 de¤erleri gruplar aras›nda anlaml› farkl› de¤ildi. NLO1/NLO2 ile mortalite ve morbidite aras›nda hem grup Y’de hem de grup K’da anlaml› fark yoktu. Sonuç: Bu çal›flmada NLO ile kalça k›r›¤› olan hastalarda mortalite ve morbidite aç›s›ndan bir iliflki oldu¤unu gösterilememifltir.