Journals / Etlik Veteriner Mikrobiyoloji Dergisi / 1996 / Cilt: 8 - Sayı: 4
Effect Of Infectious Bronchitis Virus On The Tracheal Organ Cultures: Light Microscopic Examination
- Pages
- 21–28
- DOI
- —
Abstract
Infectivity titration of IBV M4 1 strain (reference virus) were done in tracheal organ cultures and expressed as the fıfty per cent ciliostatic dose (CD50) per ml. The teter of the IBV M41 strain was log ı O 5,48 CD50/ml. Histopathological examination of virus -infected tracheal rings showed loss of kynocilum, fiattening of lamina epithelialis and pyknosis, raunding and desquamation of epithelial cell.
Özet
IBV M41 referens suşunun infektivite titrasyonu tracheal organ kültürlerinde yapıldı ve Ml'de %50 siliostatik doz olarak ifade edildi. lB M41 suşunun titresi Log10 5,48 CD50/ml idi. Virus-infekte tracheal halkaların histopatolojik incelemesinde kinosilyumlarda kayıp, epitel katmanda yassılaşma ve epitel hücrelerinde yuvarlaklaşma, piknoz ve dökülmeler gözlendi.