Synthesis and Characterization of Schiff Base 1-Amino-4-methylpiperazine Derivatives

Abstract

In this study, potentially biological active new Schiff bases were synthesized in good yield from 1-amino-4-methylpiperazine and aromatic aldehydes as a 3-nitro-benzaldehyde, 4-fluoro-benzaldehyde, 3,4,5-trimethoxybenzaldehyde, 3,4-dichlorobenzaldehyde, 4-diethylaminobenzaldehyde, 2,5-dimethoxybenzaldehyde and 5-nitro-2-furaldehyde and structure of the synthesized compounds were elucidated by FTIR, LC-MS, 1H-NMR and 13C-NMR techniques.