Journals / Türk Pediatri Arşivi / 1993 / Cilt: 28 Sayı: 1
Physiopathology and Treatment in Meningococcal Sepsis
- Journal
- Türk Pediatri Arşivi
- Pages
- 1–1
- DOI
- —
Abstract
Mortality in meningcoccal sepsis is still very high despite appropriate chemotherapy and advanced intensive care facilities Cytokines and mediators secreted after bacterial lipopolysaccaharide stimulation are responsible for hemodynamic and metabolic disorders The basic therapeutic principles are administration of antibiotics and intravenous fluids New therapeutic measures such as plasmapheresis leucopheresis and administration of anticytokines antibodies may prove effective in the future Key words: Meningococcal Sepsis Physiopathology Treatment
Özet
SummaryMortality in meningcoccal sepsis is still very high despite appropriate chemotherapy and advanced intensive care facilities Cytokines and mediators secreted after bacterial lipopolysaccaharide stimulation are responsible for hemodynamic and metabolic disorders The basic therapeutic principles are administration of antibiotics and intravenous fluids New therapeutic measures such as plasmapheresis leucopheresis and administration of anticytokines antibodies may prove effective in the future Key words: Meningococcal Sepsis Physiopathology Treatment