The HAIR-AN syndrome : a case report

Abstract

The HAIR-AN Syndrome affects about 5% of hirsute women and characterized by insulin resistance, elevated insulin levels, acanthosis nigricans(AN) and hyperandrogenism. The patient presented here is a 21 year-old woman who has secondary amenorrhea, hirsutism, and hyperpigmented skin changes. The patient was given oral contraceptive and spironolactone. After nine months, the patient was observed for significant clinical and hormonal improvement. [Journal of Turgut Özal Medical Center 2(2):204-205,1995] Key words: Acantosis nigricans, hirsutismus, insulin resistance ,oral contraceptive, spironolactone

Özet

HAIR-AN sendromu hirsut kadınların yaklaşık %5'ini etkiler ve insiilin rezistansı, yüksek insülin seviyeleri, akantosis nigrikans (AN) ve hiperandrojenizm ile karakterizedir. Burada sunulan hasta 21 yaşında bir kadın olup sekonder amenore, hirsutism ve hiperpigmente deri değişiklikleri vardı. Hastaya kontraseptif ve spironolakton verildi. Dokuz ay sonra, hastada anlamlı klinik ve hormonal iyileşme gözlendi. [Turgut Özal Tıp Merkezi Dergisi 2(2):204-205,1995] Anahtar kelimeler: Acantosis nigricans, hirsutismus, insulin resistansı ,oral kontraseptif, spironolactone

Keywords: Acantosis nigricans, hirsutismus, insulin resistansı , oral kontraseptif, spironolactone