Good's Syndrome with Pneumocystis Jiroveci Lymphadenitis and Pure Red Cell Aplasia

Abstract

Pneumocystis jiroveci lymphadenitis is a rare manifestation of extrapulmonary pneumocystosis. A case of recurrent infection with lymphadenitis caused by Pneumocystis jiroveci in a middle-aged patient is described. He presented with prolonged fever, recurrent diarrhea, and severe anemia required frequent blood transfusion recognized to be Good’s syndrome. Cervical lymph node biopsy revealed caseating granulomas and presence of organisms morphologically consistent with Pneumocystis spp. Bone marrow biopsy was compatible with pure red cell aplasia associated with Good’s syndrome. According to our knowledge, it is the first case diagnosed with Good’s syndrome, Pneumocystis jiroveci lymphadenitis and pure red cell aplasia. J Microbiol Infect Dis 2016;6(2): 87-91