Pregnancy outcome of a case with Swyer syndrome after bilateral gonadectomy and adjuvant chemotherapy

Abstract

Swyer syndrome is a rare disorder characterized by a phenotypic female with an XY karyotype. We presented a patient with Swyer syndrome with a diagnosis of malign germ cell tumor. After bilateral gonadectomy and pelvic lymph node dissection, the patient received four courses of bleomycin, etoposide and cisplatin chemotherapy. The patient was free from tumour recurrence after 13years’ follow-up. A successful pregnancy was achieved by oocyte donation and in vitro fertilization. Caesarean delivery was performed at 37 gestational weeks due to oligohydramnios and intrauterine growth restriction.