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Journals / Acta Veterinaria Eurasia / 2014 / Cilt: 40 Sayı: 2

Subtyping Canine Anal Sac Gland Adenocarcinomas by Means of Quantitative Morphology

ANAL KESE BEZİ ADENOKARSİNOMALARININ KANTİTATİF MORFOLOJİ YÖNTEMİ İLE SUBTİPLENDİRİLMESİ

Radostin SIMEONOV
Pages
243–248
Publication Date
2014-07-22
DOI
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The results of this preliminary study indicated that nuclear morphometry could be used as an auxiliary method for subtyping canine anal sac gland adenocarcinomas.Key Words: Cytology, image analysis, nuclear morphometry, histopathological subtypes, canine anal sac gland adenocarcinomas

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In this retrospective study, nuclear morphometric parameters of histopathologically confirmed anal sac gland adenocarcinomas were investigated on cytological smears in dogs and compared with the neoplastic subtype.
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Key Findings & Data:The correlation between morphometric parameters and histopathological subtype was determined using Mann-Whitney U test (Statistica 6.0, StatSoft, USA) at level of significance P<0.05.
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Conclusion & Impact:The results of this preliminary study indicated that nuclear morphometry could be used as an auxiliary method for subtyping canine anal sac gland adenocarcinomas.Key Words: Cytology, image analysis, nuclear morphometry, histopathological subtypes, canine anal sac gland adenocarcinomas
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Sitoloji · görüntü analizi · nükleer morfometri

Abstract

In this retrospective study, nuclear morphometric parameters of histopathologically confirmed anal sac gland adenocarcinomas were investigated on cytological smears in dogs and compared with the neoplastic subtype. The correlation between morphometric parameters and histopathological subtype was determined using Mann-Whitney U test (Statistica 6.0, StatSoft, USA) at level of significance P<0.05. There were statistically significant differences between all studied morphometric parameters of tubular, rosette and solid anal adenocarcinoma patterns. The results of this preliminary study indicated that nuclear morphometry could be used as an auxiliary method for subtyping canine anal sac gland adenocarcinomas.Key Words: Cytology, image analysis, nuclear morphometry, histopathological subtypes, canine anal sac gland adenocarcinomas

Özet

Bu retrospektif çalışmada, köpeklerde histopatolojik olarak doğrulanmış anal kese bezi adenokarsinomalarının nükleer morfometrik parametreleri sitolojik smear yöntemiyle incelenmiş ve neoplastik subtiple karşılaştırılmıştır. Morfometrik parametreler ve histopatolojik subtip arasındaki korrelasyon, önem derecesi P<0,05 düzeyinde Mann-Whitney U testi (Statistica 6,0, StatSoft, USA) kullanılarak belirlenmiştir. Tubüler, rozet ve kistik anal adenokarsinoma çeşitlerinin çalışılan tüm morfometrik parametreleri arasında istatistiki açıdan önemli farklılıklar bulunmuştur. Bu ön çalışmanın sonucu olarak nükleer morfometri yönteminin köpeklerde görülen anal kese bezi adenokarsinomalarının subtiplendirilmesi amacıyla yardımcı bir yöntem olarak kullanılabileceği söylenebilir.Anahtar Kelimeler: Sitoloji, görüntü analizi, nükleer morfometri, histopatolojik subtipler, kanin anal kese bezi adenokarsinomaları

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Cite This Article

SIMEONOV, R. (2014). Subtyping Canine Anal Sac Gland Adenocarcinomas by Means of Quantitative Morphology. Acta Veterinaria Eurasia, Cilt: 40 Sayı: 2, 243–248. https://ajindex.com/articles/980915

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