Journals / Acta Orthopaedica et Traumatologica Turcica / 1989 / Cilt: 23 Sayı: 1

Experimental investigation of the effects of levamisole in prophylaxis of fat embolism syndrome

Yağ embolisinde Ievamizol ile profilaksi

Pages
8–10
Publication Date
2006-09-11
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Rats which were given levamisole had high blood O2 levels and low CO2 and lipid levels than the control group.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Multipl fractures were made in rats to establish subclinical or clinical fat embolism.
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Key Findings & Data:Each group has 15 rats.
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Conclusion & Impact:Rats which were given levamisole had high blood O2 levels and low CO2 and lipid levels than the control group.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:fat embolism syndrome · prophylaxis

Abstract

Multipl fractures were made in rats to establish subclinical or clinical fat embolism. This expenrnental research was performed in two groups. Each group has 15 rats. Levamisole was given intraperitoneally to one group while saline solution was given to the second group. PO2, PCO2, pH and blood lipids of rats were measured 72 hours after injury, and lungs of rats were defected to define fat globules, histopatologically. Rats which were given levamisole had high blood O2 levels and low CO2 and lipid levels than the control group.

Özet

Sıçanlarda yapılan bu deneysel calışmada 30 sıçanda multipl kırıklar oluşturuldu. Hayvanlarda oluşan klinik veya subklinik yağ embolisi araştırıldı. 15'er sıçandan oluşan 2 grup hayvandan deney grubuna kırıak sonrası intraperitoneal olarak Levamizol, kontrol gurubuna ise serum fizyolojik verildi. Her iki gruptaki hayvanlarda, 72 saat sonra arteriyel kan gazlan ve lipid miktarları tayin edildi. Her iki grubun akciğerleri. Akut respiratuar distres sendromu'' (ARDS) yönünden histopatolojik olarak incelendi. Levamizol verilen grupta, kontrol grubuna oranla daha iyi oksijenasyon olduğu laboratuar metodları ile belirlendi.

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Cite This Article

Guven, O., Esmenli, T. (2006). Experimental investigation of the effects of levamisole in prophylaxis of fat embolism syndrome. Acta Orthopaedica et Traumatologica Turcica, Cilt: 23 Sayı: 1, 8–10. https://ajindex.com/articles/980193

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