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Journals / Acta Orthopaedica et Traumatologica Turcica / 2026 / Cilt: 48 Sayı: 1

Aggressive fibromatosis: evaluation of prognostic factors and outcomes of surgical treatment

Agresif fibromatozis: Prognostik faktörler ve cerrahi tedavi sonuçlarının değerlendirilmesi

Levent Kucuk
Burcin Kececi
Dundar Sabah
Guven Yuceturk
Pages
55–60
Publication Date
2014-03-17
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Adjuvant radiotherapy administration appears to be a rational treatment method instead of sacrificing function to achieve wide surgical margins.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: The aim of this study was to evaluate the results of surgical treatment of aggressive fibromatosis and the effects of prognostic factors on recurrence.
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Key Findings & Data:Methods: Forty patients (24 female, 16 male; average age: 31.2 years) diagnosed with aggressive fibromatosis were evaluated retrospectively.
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Conclusion & Impact:Conclusion: Adjuvant radiotherapy administration appears to be a rational treatment method instead of sacrificing function to achieve wide surgical margins.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Adjuvan radyoterapi · ekstremite koruma · nüks

Abstract

Objective: The aim of this study was to evaluate the results of surgical treatment of aggressive fibromatosis and the effects of prognostic factors on recurrence. Methods: Forty patients (24 female, 16 male; average age: 31.2 years) diagnosed with aggressive fibromatosis were evaluated retrospectively. Nine patients with tumor-positive surgical margins macroscopically were excluded. Prognostic factors such as age, gender, localization, admission status, compartment status, surgical margin, tumor size and adjuvant radiotherapy were evaluated. Results: Recurrence rate was 29%. Average disease free survival was 46±4 months. There was no statistically significant relation between prognostic factors and recurrence. Clinical results of the patients receiving adjuvant radiotherapy were more satisfactory. Conclusion: Adjuvant radiotherapy administration appears to be a rational treatment method instead of sacrificing function to achieve wide surgical margins.

Özet

Amaç: Çalışmamızın amacı agresif fibromatozisin cerrahi tedavisinin sonuçları ile nüks prognostik faktörlerin nüks gelişimi üzerine etkilerini değerlendirmekti. Çalışma planı: Agresif fibromatozis tanısı alan 40 hasta (24 kadın, 16 erkek; ortalama yaş: 31.2) retrospektif olarak değerlendirildi. Cerrahi sınırlarda makroskobik olarak pozitif tümör dokusu saptanan 9 hasta çalışma dışında bırakıldı. Çalışmada, yaş, cinsiyet, tümör yerleşimi, hastanın kliniğe başvurduğu andaki durumu, kompartman durumu, cerrahi sınır, tümör boyu ve adjuvan radyoterapi gibi prognostik faktörler değerlendirildi. Bulgular: Nüks oranı %29 olarak saptandı. Ortalama hastalıksız takip süresi 46±4 aydı. Nüks gelişimi ile prognostik faktörler arasında istatistiksel olarak anlamlı bir sonuç yoktu. Adjuvan radyoterapi uygulanan hastalardaki klinik sonuçların daha tatmin edici olduğu görüldü. Çıkarımlar: Fonksiyonun feda edilerek geniş cerrahi sınırların sağlanması yerine adjuvan radyoterapi uygulaması agresif fibromatozis tedavisi için akılcı bir yaklaşım olacaktır.

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Cite This Article

Kucuk, L., Kececi, B., Sabah, D., Yuceturk, G. (2014). Aggressive fibromatosis: evaluation of prognostic factors and outcomes of surgical treatment. Acta Orthopaedica et Traumatologica Turcica, Cilt: 48 Sayı: 1, 55–60. https://ajindex.com/articles/979070

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