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Journals / European Journal of Therapeutics / 2009 / Cilt: 15 Sayı: 3

Effect mechanism of immunosupressive drugs

İmmunsupresif ilaçların etki mekanizmaları

Tülay Kılıçaslan AYNA
Hayriye Şentürk ÇİFTÇİ
Hilmi TOZKIR
Mehmet GÜRTEKİN
Mahmut ÇARİN
Pages
42–47
Publication Date
2009-04-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These immunosuppressive agents are steroids, anti-proliferative agents (azathioprine and mycophenolate), calcineurin inhibitors .(cyclosporine and tacrolimus), TOR inhibitors (sirolimus and everolimus), polyclonal and monoclonal antibody preparations.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Effective immunosuppression is a key to successful organ transplantation.
📊
Key Findings & Data:This study will provide an overview öf different immunosuppressive agents used in solid organ transplantation.
💡
Conclusion & Impact:These immunosuppressive agents are steroids, anti-proliferative agents (azathioprine and mycophenolate), calcineurin inhibitors .(cyclosporine and tacrolimus), TOR inhibitors (sirolimus and everolimus), polyclonal and monoclonal antibody preparations.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Organ nakli · İmmün baskılayıcı ajanlar · İmmün baskılama

Abstract

Effective immunosuppression is a key to successful organ transplantation. This study will provide an overview öf different immunosuppressive agents used in solid organ transplantation. An increasing number of immunosuppressive agents are available and these agents target different steps of the immunological response to an allograft. These immunosuppressive agents are steroids, anti-proliferative agents (azathioprine and mycophenolate), calcineurin inhibitors .(cyclosporine and tacrolimus), TOR inhibitors (sirolimus and everolimus), polyclonal and monoclonal antibody preparations.

Özet

Etkili immunsupresyon, başarılı bir organ transplantasyonu için önemlidir. Burada solid organ transplantasyonunda, kullanılan farklı immunsupresif ajanlara genel bir bakış yapacağız. İmmunsupresif, ajanların sayısıgün geçtikçe artmaktadır.Bu ajanlar, alloğrafta karşı oluşan immünolojik cevabın farklı basamaklarını hedef alırlar. Bu immunsupresif ajanlar: steroidler, anti-proliferatif ajanlar (azatiyopirin and mikofenolat), kalsinörin inhibitörleri (siklosporin ve tacrolimus), TOR inhibitörleri (sirolimus ve everolimus) poliklonal ve monoklonal antikor preparasyonlarıdır.

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Cite This Article

AYNA, T. K., ÇİFTÇİ, H. Ş., TOZKIR, H., GÜRTEKİN, M., ÇARİN, M. (2009). Effect mechanism of immunosupressive drugs. European Journal of Therapeutics, Cilt: 15 Sayı: 3, 42–47. https://ajindex.com/articles/977072

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