Journals / European Journal of Therapeutics / 2013 / Cilt: 19 Sayı: 1

The evaluation of brucellosis in children in an endemic region of Turkey, Van

Türkiye'nin endemik bölgesi Van'da çocuk bruselloz hastalarının incelenmesi

Pages
1–4
Publication Date
2013-02-01
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Brucellosis is an important health issue, especially in endemic regions, necessitating preventive measures and effective treatment.

📌 3 Key Takeaways

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Objective & Hypothesis:Brucellosis is an important infectious disease especially endemic in Eastern and Southeastern Turkey.
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Key Findings & Data:Children with nonspecific findings suggestive of Brucellosis were included from September 2010 to February 2011 from the outpatient clinic.
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Conclusion & Impact:Brucellosis is an important health issue, especially in endemic regions, necessitating preventive measures and effective treatment.
🔬Design:Research Article
📍Scope:2010 Verileri
⚙️Variables:Bruselloz · çocuk · laboratuvar bulguları

Abstract

Brucellosis is an important infectious disease especially endemic in Eastern and Southeastern Turkey. In this study, we aimed to evaluate the clinical, laboratory and treatment results of Brucellosis in children. Children with nonspecific findings suggestive of Brucellosis were included from September 2010 to February 2011 from the outpatient clinic. The symptoms, physical findings and laboratory values are analyzed in 43 children who were diagnosed as Brucellosis.The mean age of children was 9.3 years (range: 4-13 years), 51%n:22) were male. Most common complaint was fatigue (100%), myalgia (100%) and weight loss (86%). Arthritis (48%), lymphadenopathy (6%), and splenomegaly (13%) has been identified. Laboratory values revealed high sedimentation rates (51%), high AST/ALT (65%), high CRP levels (72%). Brucella agglutination test was positive in all of the patients. Brucella was identified in 6% of blood cultures. All of the patients were treated with antibiotics of least two-drug combination. The relapse rate was 11% (n=5) and no mortality was observed. Brucellosis is an important health issue, especially in endemic regions, necessitating preventive measures and effective treatment.

Özet

Bruselloz özellikle ülkemizin doğu ve güneydoğu kesimlerinde endemik olarak görülen önemli bir enfeksiyon hastalığıdır. Bu makalede çocuklarda brusellozun klinik ve laboratuvar bulgularının ve tedavi sonuçlarının etkinliğini değerlendirmek amaçlandı.Eylül 2010 ile Şubat 2011 tarihleri arasında yaklaşık 6 aylık dönemde çocuk polikliniğine bruselloz düşündüren şikayetlerle başvuran çocuklar tetkik edildi. Tetkik edilen hastaların 43'üne bruselloz tanısı konuldu ve başvuru şikayetleri, fizik muayene bulguları ve laboratuvar sonuçları değerlendirildi. Olguların 22'si erkek (%51) olup ortalama yaşları 9.3 yaş (4 yaş-13 yaş) arasında idi. En sık başvuru yakınmaları; halsizlik olguların tamamı (%100), kas ağrısı olguların tamamı (%100) ve kilo kaybı (%86) idi. Olguların fizik muayenelerinde; artrit (%48), lenfadenopati (%6) ve splenomegali (%13) saptandı. Laboratuvar bulgularında olguların %51'inde sedimantasyon yüksekliği, %65'inde ALT/AST yüksekliği ve %72'sinde ise CRP pozitifliği vardı. Brusella aglütinasyon testleri olguların tamamında pozitifti. Kan kültüründe üreme olguların %6'sında tespit edildi. Olguların tamamına en az ikili antibiyotik tedavisi verildi. Rölaps %11 (n=5) oranında görüldü, mortalite gözlenmedi. Bruselloz özellikle hastalığın yaygın olduğu bölgelerde sağlık ekiplerinin üzerinde durması gereken ve koruyucu tedbirlerin alınması ve etkin tedavinin uygulanması gereken toplum sağlığı problemidir.

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Cite This Article

SARI, E., SARI, İ. Ö., SAY, A., GÜVEN, F., ULUTAŞ, A. P. (2013). The evaluation of brucellosis in children in an endemic region of Turkey, Van. European Journal of Therapeutics, Cilt: 19 Sayı: 1, 1–4. https://ajindex.com/articles/976909

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