Journals / Türk Hijyen ve Deneysel Biyoloji Dergisi / 2011 / Cilt: 68 Sayı: 3

Current situation of Crimean Congo hemorrhagic fever CCHF in Anatolia and Balkan Peninsula

Anadolu ve Balkan Yarımadası’nda Kırım Kongo kanamalı ateşi KKKA ’nin güncel durumu

Pages
139–151
Publication Date
2011-09-01
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

While Bulgaria, Kosovo and Albania were

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Crimean-Congo hemorrhagic fever CCHF is a viral disease transmitted to humans mainly by bite of Ixodid ticks, mainly those of the Hyalomma genus.
📊
Key Findings & Data:CCHF originally identified in the former Soviet Union and the Congo, has rapidly spread across large sections of Europe, Asia, and Africa, and has been reported in more than 30 countries.
💡
Conclusion & Impact:While Bulgaria, Kosovo and Albania were
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:KKKA virüsü · Balkanlar · Anadolu

Abstract

Crimean-Congo hemorrhagic fever CCHF is a viral disease transmitted to humans mainly by bite of Ixodid ticks, mainly those of the Hyalomma genus. CCHFV belongs to the genus Nairovirus in the family Bunyaviridae. CCHF virus is a segmented, single stranded, negative sense and RNA viruses. The onset of the disease is very sudden, with symptoms such as fever, rigors, intense headache, chills, and backache or leg pains, myalgia, nausea, and vomiting. CCHF originally identified in the former Soviet Union and the Congo, has rapidly spread across large sections of Europe, Asia, and Africa, and has been reported in more than 30 countries. The climatic changes may affect the life cycle of ticks and the routes of migratory birds, leading to tick abundance and virus distribution in CCHF-free areas. Extended use of land for agriculture and farming and changes in hunting activities play also a role in CCHF incidence, while livestock trade and movement may influence host-tick-virus dynamics resulting in transfer of CCHFV-infected ticks in non-endemic areas. Recent years, the epidemiology of CCHF is changing in Balkans and Turkey. Balkan Peninsula is a known endemic CCHF area, and sporadic cases and even outbreaks are being reported every year. The annual number of human CCHF cases is increasing in Balkans and Turkey. While Bulgaria, Kosovo and Albania were

Özet

Kırım-Kongo Kanamalı Ateşi KKKA , özellikle Ixodid cinsi kene ısırığı esas olarak Hyalomma cinsi tarafından insanlara bulaşan viral bir hastalıktır. CCHFV, Bunyaviridae ailesinden Nairovirus cinsine aittir. KKKA virüsü segmentli, tek iplikli, negatif polariteli bir RNA virüsüdür. Hastalığın başlangıcında ani ateş, titreme, şiddetli baş ağrısı, sırt ağrısı ya da bacak ağrıları, kas ağrısı, mide bulantısı ve kusma gibi belirtiler olabilir. KKKA, ilk olarak eski Sovyetler Birliği ve Kongo’da tespit edilmiş olup, hızlıca Avrupa, Asya ve Afrika’nın büyük bölümüne yayılmıştır ve 30’dan fazla ülkede bildirimi yapılmıştır.İklim değişiklikleri; kenelerin yaşam döngüsünü ve göçmen kuşların göç yollarını etkileyebilir, KKKA’nden yoksun bölgelere virüs yayılımında ve kene sayısının artmasında rol alabilir. Tarım ve çiftçilik için arazi kullanımının genişletilmesi ve avcılık faaliyetlerindeki değişiklikler de KKKA insidansında rol oynayabilir. Hayvan ticareti ve nakli KKKA virüsü ile enfekte kenelerin endemik olmayan bölgelere transferine neden olarak konak-kene-virüs dinamiklerini etkileyebilir. Son yıllarda, Balkanlar’da ve Türkiye’de KKKA epidemiyolojisi değişmektedir. Balkanlar endemik KKKA bölgesi olarak bilinir ve heryıl sporadik vakalar, hatta salgınlar bildirilir. Balkanlar ve Türkiye’de yıllık olarak tespit edilen insan KKKA vakalarının sayısı artmaktadır. Hastalık, Balkanlarda; Bulgaristan, Kosova ve Arnavutluk

🔖

Cite This Article

UYAR, Y., CHRİSTOVA, I., PAPA, A. (2011). Current situation of Crimean Congo hemorrhagic fever CCHF in Anatolia and Balkan Peninsula. Türk Hijyen ve Deneysel Biyoloji Dergisi, Cilt: 68 Sayı: 3, 139–151. https://ajindex.com/articles/975644

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Papa A. Crimean-Congo hemorrhagic fever and hantavirus infections. In: Maltezou H, Gikas A, editors. Tropical and Emerging Infectious Diseases. Kerala, India: Research Signpost; 2010. p. 49-73
  2. Chumakov MP. A new tick-borne virus disease— Crimean hemorrhagic fever (acute infectious capillary toxicosis) In: Sokolov AE, Chumakov MP, Kolachev AA, editors. Crimean Hemorrhagic Fever (Acute Infectious Capillary Toxicosis). Izdanie Otdel’noj Primorskoj Armii, Simferopol. USSR 1945. p. 13-43
  3. Simpson DI, Knight EM, Courtois G, Williams MC, Weinbren MP, Kibukamu- soke JW. Congo virus: a hitherto undescribed virus occurring in Africa I. Human isolations—clinical notes. East Afr Med J, 1967; 44: 86-92
  4. Simpson DIH, Williams MC, Woodal IP. Four cases of human infection with the Congo agent East Afr Virus Res Inst Rep. 1965: 27-8
  5. Casals J. Antigenic similarity between the virus causing Crimean hemorrhagic fever and Congo virus. Proc Soc Exp Biol Med, 1969; 131(1): 233-6
  6. Woodall JP, Williams MC, Simpson DI. Congo virus – a hitherto undescribed virus occurring in Africa. II. Identification studies East Afr Med J, 1967; 44: 93-8
  7. Hoogstraal H. The epidemiology of tick-borne Crimean-Congo hemorrhagic fever in Asia, Europe, and Africa. J Med Entomol, 1979;15(4): 307-417
  8. Butenko AM, Karganova G. Crimean-Congo Hemorrhagic Fever in Russia and other countries of the former Soviet Union. In: Ergonul O, Whitehouse CA, editors. Crimean Congo Hemorrhagic Fever. A Global Perspective. Dordrecht: Springer; 2007. p. 99-114
  9. Yen YC, Kong LX, Lee L, Zhang YQ, Li F, Cai BJ, et al. Characteristics of Crimean-Congo hemorrhagic fever virus (Xinjiang strain) in China. Am J Trop Med Hyg, 1985; 34(6): 1179-82
  10. Anagnostou V, Papa A. Evolution of Crimean-Congo Hemorrhagic Fever virus. Infect Genet Evol, 2009; 9(5): 948-54
  11. Carroll SA, Bird BH, Rollin PE, Nichol ST. Ancient common ancestry of Crimean-Congo hemorrhagic fever virus. Mol Phylogenet Evol, 2010; 55(3): 1103-10 12. Schmaljohn CS, Nichol ST. Bunyaviridae. In Fields Virology, Edited by: Knipe DM, Howley PM. Philadelphia: Lippincott, Williams and Wilkins, 5th edition. 2007; Volume 2: 1741-89
  12. Karlberg H, Tan YJ, Mirazimi A. Induction of caspase activation and cleavage of the viral nucleocapsid protein in different cell types during CrimeanCongo hemorrhagic fever virus infection. J Biol Chem, 2011; 286(5): 3227-34
  13. Papa A, Ma B, Kouidou S, Tang Q, Hang C, Antoniadis A. Genetic characterization o