SavedAdd your journal

Journals / The European Research Journal / 2023 / Cilt: 9 Sayı: 5 - September 2023

Prognostic value of the leuko-glycemic index in coronary chronic total occlusion patients

Tezcan PEKER
Mehmet ÖZBEK
Bedrettin BOYRAZ
Selen Filiz ASLAN
Muhammed DEMİR
Burhan ASLAN
Pages
1099–1104
Publication Date
2023-09-04
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusions: The study revealed that high LGI is associated with all-cause death in CTO patients and LGI was a predictor of all-cause death.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: Inflammation parameters are related to the prevalence and mortality of coronary artery disease (CAD).
📊
Key Findings & Data:Methods: A total of 546 patients were evaluated in the study.
💡
Conclusion & Impact:Conclusions: The study revealed that high LGI is associated with all-cause death in CTO patients and LGI was a predictor of all-cause death.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Leuko-glycemic index · coronary total occlusion · mortality

Abstract

Objectives: Inflammation parameters are related to the prevalence and mortality of coronary artery disease (CAD). We aimed to evaluate the prognostic value of the leuko-glycemic index (LGI) and determine mortality in patients with chronic coronary total occlusion (CTO). Methods: A total of 546 patients were evaluated in the study. All-cause death was the primary endpoint. The leuko-glycemic index was calculated from the blood samples at admission and patients were divided into 3 groups according to their LGI levels. Kaplan-Meier survival curves were performed and logistic regression analyses was used for all multivariable analysis. Results: The mean age of the study population was 63.1 ± 11.1 years and 70.3% were male. Median follow-up time 58.2 ± 22.4 months. The mortality rate was 33.6% in the high LGI group and significantly higher compared to the other group. In multivariable analysis, LGI (OR: 1.05, 95% CI: 1,0-1.2; p = 0.02) and age (OR: 1.07, 95% CI: 1.04-1.11; p = 0.001) were found as predictors of all-cause death. Conclusions: The study revealed that high LGI is associated with all-cause death in CTO patients and LGI was a predictor of all-cause death.

🔖

Cite This Article

PEKER, T., ÖZBEK, M., BOYRAZ, B., ASLAN, S. F., DEMİR, M., ASLAN, B. (2023). Prognostic value of the leuko-glycemic index in coronary chronic total occlusion patients. The European Research Journal, Cilt: 9 Sayı: 5 - September 2023, 1099–1104. https://ajindex.com/articles/960985

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. Roth GA, Mensah GA, Johnson CO, Addolorato G, Ammirati E, Baddour LM, et al. Global Burden of Cardiovascular Diseases and Risk Factors, 1990-2019: Update From the GBD 2019 Study. J Am Coll Cardiol 2020;76:2982-3021
  2. Sianos G, Barlis P, Di Mario C, Papafaklis MI, Büttner J, Galassi AR, et al. European experience with the retrograde approach for the recanalisation of coronary artery chronic total occlusions. A report on behalf of the euroCTO club. EuroIntervention 2008;4:84-92
  3. Jeroudi OM, Alomar ME, Michael TT, El Sabbagh A, Patel VG, Mogabgab O, et al. Prevalence and management of coronary chronic total occlusions in a tertiary Veterans Affairs hospital. Catheter Cardiovasc Interv 2014;84:637-43
  4. Claessen BE, van der Schaaf RJ, Verouden NJ, Stegenga NK, Engstrom AE, Sjauw KD, et al. Evaluation of the effect of a concurrent chronic total occlusion on long-term mortality and left ventricular function inpatients after primary percutaneous coronary intervention. JACC Cardiovasc Interv 2009;2:1128-34
  5. Hoebers LP, Vis MM, Claessen BE, Van der Schaaf RJ, Kikkert WJ, Baan J Jr, et al. The impact of multivessel disease with and without a co-existing chronic total occlusion on short- and long-term mortality in ST-elevation myocardial infarction patients with and without cardiogenic shock. Eur J Heart Fail 2013;15:425-32
  6. Allahwala UK, Jolly SS, Džavík V, Cairns JA, Kedev S, Balasubramanian K, et al. The presence of a CTO in a non-infarct-related Artery during a STEMI treated with contemporary primary PCI is associated with increased rates of early and late cardiovascular morbidity and mortality: the CTO-TOTAL substudy. JACC Cardiovasc Interv 2018;11:709-711
  7. Libby P, Ridker PM, Maseri A. Inflammation and atherosclerosis. Circulation 2002;105:1135-43
  8. Yang YL, Wu CH, Hsu PF, Chen SC, Huang SS, Chan WL, et al. Systemic immune-inflammation index (SII) predicted clinical outcome in patients with coronary artery disease. Eur J Clin Invest 2020;50:e13230
  9. Arbel Y, Finkelstein A, Halkin A, Birati EY, Revivo M, Zuzut M, et al. Neutrophil/lymphocyte ratio is related to the severity of coronary artery disease and clinical outcome in patients undergoing angiography. Atherosclerosis 2012;225:456-60
  10. Li C, Zhang F, Shen Y, Xu R, Chen Z, Dai Y, et al. Impact of neutrophil to lymphocyte ratio (NLR) index and its periprocedural change (NLRΔ) for percutaneous coronary intervention in patients with chronic total occlusion. Angiology 2017;68:640-46. 11.