Journals / Interdisciplinary Medical Journal / 2023 / Cilt: 14 Sayı: 49

Determination of 25 hydroxyvitamin D reference ranges in Hatay region by indirect method

Pages
140–144
Publication Date
2023-08-31
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It can be said that the results of our region will contribute to the studies to be carried out on the determination of 25(OH)D levels and reference ranges throughout the country.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of this study is to determine the reference ranges of 25 hydroxyvitamin D (25(OH)D) levels from the serum 25(OH)D results of the patients and to investigate variations across age and gender groups.
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Key Findings & Data:Methods: The patients (n=26829) who applied to Hatay Mustafa Kemal University Hospital between January 2018 and December 2019 and whose 25(OH)D levels were studied were included in this retrospective study.
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Conclusion & Impact:It can be said that the results of our region will contribute to the studies to be carried out on the determination of 25(OH)D levels and reference ranges throughout the country.
🔬Design:Research Article
📍Scope:2018 Verileri
⚙️Variables:Vitamin D · Vitamin D Deficiency · Laboratory Tests

Abstract

Objective: The aim of this study is to determine the reference ranges of 25 hydroxyvitamin D (25(OH)D) levels from the serum 25(OH)D results of the patients and to investigate variations across age and gender groups. Methods: The patients (n=26829) who applied to Hatay Mustafa Kemal University Hospital between January 2018 and December 2019 and whose 25(OH)D levels were studied were included in this retrospective study. Serum 25(OH)D levels were studied by the chemiluminescence immunoassay method. The hospital information management system was used to obtain the test results and patient data. The indirect method was used to determine the reference ranges. Results: The prevalence of 25(OH)D deficiency in the patients participating in this study was 60.9% in the general population, 54.9% in men, and 67.5% in women. It has been observed that 25(OH)D deficiency is more common in women than in men. The reference ranges determined in this study were lower than the reference ranges provided by the manufacturer. Conclusion: In this study, 25(OH)D levels and reference ranges of Hatay Region were determined in a very large population. It can be said that the results of our region will contribute to the studies to be carried out on the determination of 25(OH)D levels and reference ranges throughout the country.

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Cite This Article

OĞUZMAN, H., DOĞAN, S. (2023). Determination of 25 hydroxyvitamin D reference ranges in Hatay region by indirect method. Interdisciplinary Medical Journal, Cilt: 14 Sayı: 49, 140–144. https://ajindex.com/articles/960759

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References (4)

  1. Cashman KD. Vitamin D Deficiency: Defining, Prevalence, Causes, and Strategjes of Addressing. Calcif Tissue Int. 2020 Jan;106(1):1 4-29. doi: 10.1007/s00223-0l9-00559-4. Epub 2019 May 8. Sempos CT, Heijboer AC, Bikle DD, Bollerslev J, Bouillon R, Brannon PM, DeLuca HF, Jones G, Munns CF, Bilezikian JP, Giustina A, Binkley N. Vitamin D assays and the definition of hypovitaminosis D: results from the First International Conference on Controversies in Vitamin D. Br J Clin Pharmacol. 2018 Oct;84(10):2194-2207. doi: 10.1111 /bcp.13652. Epub 2018 Jul 17. Börekçi NÖ. Current infonnation on vitamin D deficiency. Jour Tuk Fam Phy 2019;10(1):35-42. doi:10.15511 /jtfp.19.00135 Amrein K, Scherkl M, Hoffmann M, Neuwersch-Sommeregger S, Kostenberger M, Tmava Berisha A, Martucci G, Pilz S, Malle O. Vitamin D deficiency 2.0: an update on the current status worldwide. Eur J Clin Nutr. 2020 Nov;74(11): 1498-1513. doi: 10.1038/s41430-020- 0558-y. Epub 2020 Jan 20. PMID: 31959942; CLSI. Defining, Establishing, and Verifying Reference Intervals in the Clinical Laboratory; Approved Guideline-Third Edition. CLSI Document C28-A3. Wayne, PA, USA: Clinical and Laboratory Standards Institute; 2008.
  2. Çaycı T, Kurt YG, Honca T, Taş A, Özgürtaş T, Ağıllı M, Aydn FN, Aydın İ. Hastane bilgi sistemindeki kayıtlı hasta sonuçlarından tam kan referans aralıklarının tayini. Gülhane Tıp Derg 2015; 57: I 11-117. doi: 10.5455/gulhane. 167492 Aydın İ, Ağıllı M, Aydın FN, Kurt YG, Çaycı T, Taş A, Honca T, Özgürtaş T, Türker Türker, Koçak N. Farklı yaş gruplarında nötrofil/lenfosit oranı referans aralıkları. Gülhane Tıp Derg 2015;57: 414-418. doi: 10.5455/gulhane. 166398 Çatak Z. Elazığ Bolgesinin 25 Hidroksivitamin D Düzeylerinin Değerlendirilmesi ve Populasyona Dayalı Yeni Referans Aralıklarının Belirlenmesi. Fırat Tıp Dergisi/Firat Med J 2018; 23 (1): 6-10.
  3. Alpdemir M, Alpdemir MF. Determination of reference range with the indirect method of the 25- hydroxyvitamin D3 test in the Balıkesir region, Turkey. Turk J Med Sci (2016)46:1 512 -1517. doi: 10.3906/sag-1504-19. Solberg HE. International Federation of Clinical Chemistry (JFCC), Scientific Committee, Clinical Section, Expert Panel on Theory of Reference Values, and International Committee for Standardization in Haematology (JCSH), Standing Committee on Reference Values. Approved recommendation (1986) on the theory of reference values. Part 1. The concept of reference values. J Clin Chem Clin Biochem 1987; 25: 337-342.
  4. Öztürk ZA, Gol M, Türkb