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Journals / Gazi University Journal of Science / 2023 / Cilt: 36 Sayı: 3

The Study of Interaction Activity of Nickel (ll) Phthalocyanine Complex Bearing Tetra Substituted Phenoxy-3-Methoxybenzoic Acid Groups with DNA

Ali ARSLANTAS
Mehmet Salih AĞIRTAŞ
Pages
1022–1032
Publication Date
2023-09-01
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Further, the interacting activity of PcNi on the DNA was analyzed by which electrophoresis technique and this procedure indicated that PcNi complex exhibits strong binding affinity on the DNA.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Nickel phthalocyanine complex containing 3-methoxybenzoic acid groups was acquired and specified by way of Fourier Transform Infrared, NMR and UV-Visble spectroscopy procedures.
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Key Findings & Data:The interaction activity of PcNi against the DNA was examined by way of absorption spectra titrations and the fluorescence spectra, farther by conducting melting point, viscosity procedures in the buffer of a pH 7.02.
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Conclusion & Impact:Further, the interacting activity of PcNi on the DNA was analyzed by which electrophoresis technique and this procedure indicated that PcNi complex exhibits strong binding affinity on the DNA.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Calf thymus-DNA · Phthalocyanines · UV/Vis Spectroscopy

Abstract

Nickel phthalocyanine complex containing 3-methoxybenzoic acid groups was acquired and specified by way of Fourier Transform Infrared, NMR and UV-Visble spectroscopy procedures. Interaction of PcNi with the DNA molecule was examined via electronic absorption spectra, fluorescence spectra, melting point, viscosity, and the electrophoresis technics, respectively. The interaction activity of PcNi against the DNA was examined by way of absorption spectra titrations and the fluorescence spectra, farther by conducting melting point, viscosity procedures in the buffer of a pH 7.02. The obtained outcomes from these methods demonstrated that PcNi indicated substantial binding affinity to the DNA via intercalating by Kb of 1.31 x 106 m-1. Further, the interacting activity of PcNi on the DNA was analyzed by which electrophoresis technique and this procedure indicated that PcNi complex exhibits strong binding affinity on the DNA.

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Cite This Article

ARSLANTAS, A., AĞIRTAŞ, M. S. (2023). The Study of Interaction Activity of Nickel (ll) Phthalocyanine Complex Bearing Tetra Substituted Phenoxy-3-Methoxybenzoic Acid Groups with DNA. Gazi University Journal of Science, Cilt: 36 Sayı: 3, 1022–1032. https://ajindex.com/articles/960512

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