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Journals / Van Sağlık Bilimleri Dergisi / 1998 / Cilt: 4 Sayı: 1-2

The Efect of The Hyperthyroidism on The Levels of Lipid Peroxidatioıı, Glutathione and Lipid-Bouııd Sialic Acid in The Rabbids

Hipertiroidizmin Tavşanlarda Lipid Peroksidasyon, Glutatyon ve Lipid-Bağlı Sialik Asit Seviyeleri Üzerine Etkisi

Burhanettin Baydaş
Ali Ertekin
Fatmagül Yur
Ferda Belge
Fahri Bayıroğlu
Pages
5–8
Publication Date
1998-06-14
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

İn the treatment group compaired to the control, lipid peroxidation, GSH and LSA levels were found to be elevated significantly lipid peroxidation and LSA P

📌 3 Key Takeaways

🎯
Objective & Hypothesis:This study was planned to investigate the effect of hyperthyroidism on blood lipid peroxidation, glutathione GSH and lipid-bound sialic acid LSA levels.
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Key Findings & Data:Hyperthyroidism was produced by administration of thyroxine 100 pg/kg body yveight i.p , for 30 consecutive days.
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Conclusion & Impact:İn the treatment group compaired to the control, lipid peroxidation, GSH and LSA levels were found to be elevated significantly lipid peroxidation and LSA P
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Hipertiroidizm · Lipid peroksidasyon · GSH

Abstract

This study was planned to investigate the effect of hyperthyroidism on blood lipid peroxidation, glutathione GSH and lipid-bound sialic acid LSA levels. Sixteen rabbits Lepus europous was used in this study. Rabbits divided two groups as control and treatment. Hyperthyroidism was produced by administration of thyroxine 100 pg/kg body yveight i.p , for 30 consecutive days. Following treatment, thyroid hormone levels were measured in the treatment and control groups. In the treatment group, triiodothyronine T3 and thyroxine T4 levels were found to be increased signifıcantly T3 91.6±5.7-288.4±17 ng/dl, TT4 3.88±0.60-8.42±l.4 pg/dl . Lipid peroxidation and GSH levels were determined in whole blood, while LSA evaluating in serum. İn the treatment group compaired to the control, lipid peroxidation, GSH and LSA levels were found to be elevated significantly lipid peroxidation and LSA P

Özet

Bu çalışma, hipertiroidizmin lipid peroksidasyon, glutatyon GSH ve lipid-bağlı sialik asit LSA seviyeleri üzerine etkisini araştırmak amacıyla planlandı. Çalışmada 16 adet tavşan Lepus europous kullanıldı. Tavşanlar deney ve kontrol grubu olmak üzere ikiye ayrıldı. Hipertiroidizm, otuz giın süreyle 100 pg/kg dozunda tiroksin i.p uygulamasıyla oluşturuldu. Bu süre sonunda deney ve kontrol grubu tavşanlarda tiroid hormonları düzeylerine bakıldı. Deney grubunda tiroksin TT4 ve triiodotironin TT3 seviyeleri oldukça yüksek düzeyde bulundu TT3 91.6±5.7-288.4±17 ng/dl, TT4 3.88±0.60-8.42±1.4 pg/dl . Lipid peroksidasyon ve GSH tayini için tüm kan, LSA ölçümü için serum kullanıldı. Kontrol grubu ile karşılaştırıldığında, hipertiroidili grupta hem lipid peroksidasyon ve LSA P

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Cite This Article

Baydaş, B., Ertekin, A., Yur, F., Belge, F., Bayıroğlu, F. (1998). The Efect of The Hyperthyroidism on The Levels of Lipid Peroxidatioıı, Glutathione and Lipid-Bouııd Sialic Acid in The Rabbids. Van Sağlık Bilimleri Dergisi, Cilt: 4 Sayı: 1-2, 5–8. https://ajindex.com/articles/953067

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