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Journals / Current Perspectives on Medicinal and Aromatic Plants / 2023 / Cilt: 6 Sayı: 1

Anticholinesterase, Antidiabetic and Antioxidant Activities of Chloroform Extract of Genista carinalis

Hilmican ÇALIŞKAN
Hakime Hülya ORAK
Cansel CAKIR
Merve ARGON
Temine ŞABUDAK
Mehmet ÖZTÜRK
Necmettin GÜLER
Pages
1–6
Publication Date
2023-07-02
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The EC50 value of DPPH assays for extract was found to be 0.101 μg/ml.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Alzheimer's disease, diabetes has become an increasing public health issues in recent years.
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Key Findings & Data:The TEAC value was determined to be 0.484 mmol TE/g, FRAP value was found to be 1023.20 µmol Fe2+/g for G. carinalis chloroform extract.
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Conclusion & Impact:The EC50 value of DPPH assays for extract was found to be 0.101 μg/ml.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Genista · G. carinalis · Anticholinesterase activity

Abstract

Alzheimer's disease, diabetes has become an increasing public health issues in recent years. On the other hand, synthetic drugs are expensive, could be inadequate to treat diseases, could be cause irritation, and side effects. Therefore, increasingly more researchis being done to plant-derived formulas, bioactive ingredients, which can be an alternative to synthetic drugs for treatments to solve basic health problems. In this study the antioxidant, anticholinesterase and antidiabetic activities of G. carinalis in the chloroform extract were determined. Based on the results, the extract was not observed inhibitory activities of α-glucosidase and α-amylase. It showed better activity for acetylcholiesterase activity than the butylrylcholinesterase activity. The antioxidant potential of G. carinalis chloroform extract was determined with different assays. The TEAC value was determined to be 0.484 mmol TE/g, FRAP value was found to be 1023.20 µmol Fe2+/g for G. carinalis chloroform extract. The EC50 value of DPPH assays for extract was found to be 0.101 μg/ml.

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Cite This Article

ÇALIŞKAN, H., ORAK, H. H., CAKIR, C., ARGON, M., ŞABUDAK, T., ÖZTÜRK, M., GÜLER, N. (2023). Anticholinesterase, Antidiabetic and Antioxidant Activities of Chloroform Extract of Genista carinalis. Current Perspectives on Medicinal and Aromatic Plants, Cilt: 6 Sayı: 1, 1–6. https://ajindex.com/articles/951976

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