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Journals / Genel Tıp Dergisi / 2023 / Cilt: 33 Sayı: 3

Is There Any Correlation Between the Systemic Immune Inflammatory Index and Disease Severity in Knee Osteoarthritis?

Diz Osteoartritinde Sistemik İmmün İnflamatuar İndeks Hastalık Şiddeti ile Alakalı mıdır?

Savaş KARPUZ
Ramazan YILMAZ
Mehmet ÖZKAN
İsmail Hakkı TUNÇEZ
Eser KALAOĞLU
Halim YILMAZ
Pages
305–308
Publication Date
2023-06-30
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: The systemic immune-inflammation index was not found to be correlated with disease severity in knee OA.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective:The purpose of this study is to investigate the utility of systemic immune inflammation index as a predictor of disease severity in patients with knee osteoarthritis.
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Key Findings & Data:Methods: 200 patients diagnosed with knee osteoarthritis according to ACR knee osteoarthritis diagnostic criteria were included in the study.
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Conclusion & Impact:Conclusion: The systemic immune-inflammation index was not found to be correlated with disease severity in knee OA.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Diz osteoartriti · Enflamasyon mediatörleri · Hastalık şiddeti

Abstract

Objective:The purpose of this study is to investigate the utility of systemic immune inflammation index as a predictor of disease severity in patients with knee osteoarthritis. Methods: 200 patients diagnosed with knee osteoarthritis according to ACR knee osteoarthritis diagnostic criteria were included in the study. Kellgren-Lawrence staging of knee osteoarthritis, Western Ontario and McMaster University Osteoarthritis (WOMAC) index score and systemic immune-inflammation index score were calculated among all participants Results: There were 152 (%76) female and 48 (%24) male participants and median score of age was 63 (54,25-70). 14 (7%) grade 1 gonarthrosis, 64 (32%) grade 2, 72 (36%) grade 3 and 50 (25%) grade 4 gonarthrosis patients were detected. There was no significant correlation between the systemic immune-inflammation index and the radiological stage of gonarthrosis (Kellgren Lawrens Score) (p=0.238). No statistically significant correlation was found between the systemic immune-inflammation index and WOMAC scores (p=0.593). Conclusion: The systemic immune-inflammation index was not found to be correlated with disease severity in knee OA.

Özet

Amaç: Bu çalışmanın amacı diz osteoartiriti olan hastalarda sistemik immün enflamasyon indeksinin hastalık şiddetinin belirleyicisi olarak kullanılabilirliği araştırmaktır. Yöntem: Çalışmaya ACR diz osteoarttriti tanı kriterlerine göre gonartroz tanısı almış 200 hasta çalışmaya dahil edildi. Tüm katılımcıların diz osteoartriti Kellgren-Lawrence evrelendirmesi, Western Ontario ve McMaster Üniversitesi Osteoartrit(WOMAC) indeksi skoru ve sistemik immün-enflamasyon indeksi belirlendi. Bulgular: Katılımcıların 152’si (%76) kadın 48’si (%24) erkek ve yaş medianı 63 (54,25-70) idi. Katılımcılardan 14 (%7) kişide evre 1, 64 (%32) kişide evre 2, 72 kişide (%36) evre 3 ve 50 (%25) kişide evre 4 gonartroz tespit edildi. Sistemik immün-enflamasyon indeksi ile gonartroz radyolojik evresi (Kellgren Lawrens Skoru) arasında anlamlı ilişki tespit edilmedi (p=0,238). Sistemik immün-enflamasyon indeksi ile WOMAC skorları arasında istatistiksel anlamlı korelasyon tespit edilmedi (p=0,593). Sonuç: Sistemik immün-enflamasyon indeksi diz OA’inde hastalık şiddeti ile körele olmadığı tespit edilmiştir.

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Cite This Article

KARPUZ, S., YILMAZ, R., ÖZKAN, M., TUNÇEZ, İ. H., KALAOĞLU, E., YILMAZ, H. (2023). Is There Any Correlation Between the Systemic Immune Inflammatory Index and Disease Severity in Knee Osteoarthritis?. Genel Tıp Dergisi, Cilt: 33 Sayı: 3, 305–308. https://ajindex.com/articles/951537

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