SavedAdd your journal

Journals / Van Sağlık Bilimleri Dergisi / 2006 / Cilt: 9 Sayı: 1

The biological effects of interleukıns

İnterlökinlerin biyolojik etkileri

Feyyaz ÖNDER
Ercan KESKİN
Pages
127–138
Publication Date
2006-01-01
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review. current knowledge about the biological effects of interleukins has been given

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Cvtokines are regülatör}’ molecules in structures of peptide and glvcoprotein produced bv activated monocyte, macrophage, lymphocyte and the other cells.
📊
Key Findings & Data:Cvtokines increase cells functioning in immunity and inflammatory proccss and their effects are local or systemic.
💡
Conclusion & Impact:In this review. current knowledge about the biological effects of interleukins has been given
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:İnterlökinler · Biyolojik etki · interleukins

Abstract

Cvtokines are regülatör}’ molecules in structures of peptide and glvcoprotein produced bv activated monocyte, macrophage, lymphocyte and the other cells. Cvtokines increase cells functioning in immunity and inflammatory proccss and their effects are local or systemic. Cvtokines include groups of molecules such as interleukins, interferons, colony stimulating factors and a varietv of growth factors. In this review. current knowledge about the biological effects of interleukins has been given

Özet

Sitokinler, etkin monosit, makrofaj, lenfosit ve diğer hücreler tarafından üretilen peptid veya glikoprotein yapısında düzenleyici moleküllerdir. Bağışıklık veya yangısel olaylarda görev yapan hücrelerin etkinliklerini artıran sitokinler, etkilerini sistemik veya lokal olarak gösterirler. Sitokinler; interlökinler. interferonlar. koloni stimiilan faktörler ve çeşitli büyüme faktörleri gibi molekül gruplarından oluşmaktadır. Bu derlemede interlökinlerin biyolojik etkileri hakkında bilgi verilmiştir

🔖

Cite This Article

ÖNDER, F., KESKİN, E. (2006). The biological effects of interleukıns. Van Sağlık Bilimleri Dergisi, Cilt: 9 Sayı: 1, 127–138. https://ajindex.com/articles/947724

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (20)

  1. Trotta PP: Cytokines: An Overview. Anı J Repro Immunol 25:137-141,(1991)
  2. Akyol G, Şengil, Z, Baysal B:İnterlökinler. S Ü Tıp Fak Derg 10:117-123,(1994)
  3. Arda M, Minbay A, Aydın N, Akay Ö, İzgür M. Diker KS: İmmünoloji, Medisan Yayınevi. Medisan Yayın Serisi No: 13. Ankara. (1994)
  4. Abbas AK. Lichtman AH. Pober JS: Cellular and molecular immunology: Philadelphia: W.B. Saunders Company. (1991)
  5. Szelenyi J: Cytokines and the Central nervous system. Brain Res Bull 54:329-338, (2001)
  6. Stein RC, D a 1 g 1 e i s h AG: Immunomodulatory agents: The cytokines. Euro J Cancer 30A: 400-404. (1994)
  7. Rees RC: Cytokines as biological response modifıers. J Clin Pathol 45: 93-98, (1992)
  8. Dunn AJ. Wang J, Ando T: Effects of cytokines on cerebral neurotransmission. Adv Exp MedBiol 461:117-127.(1999)
  9. Imura H. Fukata J, Mori T: Cytokines and endocrine funetion: An interaetion between the immune and neuroendocrine Systems. Clin Immunol35:107-115,(1991)
  10. Grimble R: Inflammation. cytokines and nutrition. Euro J Clin Nutr 45:413-417. (1991)
  11. Smith KA: Interleukin-2.inception, impact and implication. Science 240: 1169-1176. (1988)
  12. Lindemann A. Mertelsmann R: Interleukin-3: Structure and funetion. Cancer Invest 11:609- 623.(1993)
  13. Gessner A, Rollinghoff M: Biologic funetions and signalling of the interleukin-4 receptor complexes. Immunobiology 201: 2 8 5-3 07. (2000)
  14. LorentzA. Bischoff SC: Regulation of human intestinal mast cells by stem celi factor and IL-4. Immunol Rev 179:57-60. (2001)
  15. Babiuk LA. Sordillo MC. Hughes HPA. RossiCampos A. Harlan R: Symposium: Immunobiology of cytokines and their application in disease prevention in dairy cattle. 74: 4385- 4398.(1991)
  16. Oswald IP. Grazzinelli RT. Sher A. James SL: IL10 synergies with IL-4 and transforming growth factor-beta to inhibit maerophage cytotoxic aetivity. J Immunol 148: 3578-3585.(1992)
  17. Mahanty S. Nutman TB: The biology of interleukin-5 and its receptor. Cancer Invest 11:5. 624-634.(1993)
  18. Lalani T. Simmons RK. Ahmed AR: Biology of IL-5 in health and disease. Ann Allergy Asthma Immunol 82:317-332. (1999)
  19. Fujisawa T. Abu-Ghazaleh R. Kita II, Sanderson CJ. Gleich GJ: Regulatorv effect of cytokines on eosinophil degranulation. J Immunol 144:642- 646.(1990)
  20. Yokota T. Coffman RL. Hagiawara H. Rennick DM. Takebe Y. Yokota K. Gemmell L. Shrader B. Yang G. Meverson P. Luh J. Hoy P. Pene J, Briere F. Spits H. Bancherua J. de Vries J. Lee FD. Arai. N. Arai.