AI Summary & Key Takeaways
AI InsightIn fact, this suggests that all HSP patients should be carefully monitored for renal involvement.
📌 3 Key Takeaways
Abstract
Background: To evaluate the demographic, clinical and laboratory characteristics of patients with Henoch-Schönlein purpura (HSP) and compare the risk of renal involvementMaterials and Methods: The files of the patients who were diagnosed as HSP in the pediatric nephrology-rheumatology clinic of our hospital between January 2015 and January 2017 and followed for at least 1 year were reviewed. Demographic data, history, age at diagnosis, physical examination, laboratory tests, organ involvement, renal biopsies, all treatment regimens and follow-up were evaluated.Results: There were 118 patients 57 male (48.3%), 61 female (51.7%) in a 2-year period. The mean age of the patients was 7.9 ± 2.81 and the female: male ratio was 1: 0.93. While there were 98 patients (83.1%) under 10 years of age, the number of patients over 10 years of age was 20 (16.9%). There was no significant relationship between age, sex, recurrence of disease, location and duration of joint involvement, location and duration of rash, gastrointestinal involvement, testicular involvement, laboratory parameters and renal involvement.Conclusion: When we retrospectively evaluated the patients, who were followed up with the diagnosis of HSP over a two-year period, we did not find any significant factor in the risk factors for renal involvement. In fact, this suggests that all HSP patients should be carefully monitored for renal involvement.
Özet
Amaç: Henoch-Schönlein purpurası (HSP) tanısı ile izlenen hastaların demografik, klinik ve laboratuvar özelliklerini değerlendirmek ve böbrek tutulumu riski açısından karşılaştırmak Materyal ve metod: Ocak 2015-Ocak 2017 tarihleri arasında hastanemiz çocuk nefroloji-romatoloji polikliniğinde HSP tanısı konup en az 1 yıl süre ile izlenen hastaların dosyaları gözden geçirildi. Demografik veriler, öykü, tanı yaşı, fizik muayene, laboratuvar tetkikleri, organ tutulumları, böbrek biyopsileri, tüm tedavi rejimleri ve izlemleri değerlendirildi. Bulgular: Çalışmamızda 2 yıllık süre içinde 57’si erkek (% 48.3) 61’i kız (% 51.7) toplam 118 hasta vardı. Hastaların yaş ortalaması 7.9 ± 2.81, kız: erkek oranı 1: 0.93 idi. 10 yaş altında 98 hasta (% 83.1) varken, 10 yaş üzeri hasta sayısı 20 (% 16.9) idi. Hastalarda yaş, cinsiyet, hastalık tekrarı, eklem tutulumu yeri ve süresi, döküntünün yeri ve süresi, gastrointestinal tutulum, testis tutulumu, laboratuar parametreleri ile böbrek tutulumu karşılaştırıldığında anlamlı bir ilişki saptanmadı. Sonuç: İki yıllık süre içinde HSP tanısı ile izlediğimiz hastaları geriye dönük olarak değerlendirdiğimizde böbrek tutulumu açısından risk faktörlerine baktığımızda anlamlı bir faktör tespit edemedik. Aslında bu durum bize tüm HSP hastalarının dikkatli bir biçimde renal tutulum açısından takip edilmesi gerektiğini düşündürmektedir. Abstract Background: To evaluate the demographic, clinical and laboratory characteristics of patients with Henoch-Schönlein purpura (HSP) and compare the risk of renal involvement Materials and Methods: The files of the patients who were diagnosed as HSP in the pediatric nephrology-rheumatology clinic of our hospital between January 2015 and January 2017 and followed for at least 1 year were reviewed. Demographic data, history, age at diagnosis, physical examination, laboratory tests, organ involvement, renal biopsies, all treatment regimens and follow-up were evaluated. Results: There were 118 patients 57 male (48.3%), 61 female (51.7%) in a 2-year period. The mean age of the patients was 7.9 ± 2.81 and the female: male ratio was 1: 0.93. While there were 98 patients (83.1%) under 10 years of age, the number of patients over 10 years of age was 20 (16.9%). There was no significant relationship between age, sex, recurrence of disease, location and duration of joint involvement, location and duration of rash, gastrointestinal involvement, testicular involvement, laboratory parameters and renal involvement. Conclusion: When we retrospectively evaluated the patients whom were followed up with the diagnosis of HSP over a two-year period, we did not find any significant factor in the risk factors for renal involvement. In fact, this suggests that all HSP patients should be carefully monitored for renal involvement.