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Journals / International Journal of Traditional and Complementary Medicine Research / 2023 / Cilt: 4 Sayı: 1

Investigating the Astonishing Antimicrobial Potential of Papaya seeds against Salmonella spp and Candida albicans

Emmanuel OBOH
Daniel ASHEFO
Peace OLEGHE
Oritseomaemimi OJEİ
Pages
26–30
Publication Date
2023-04-21
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As a result, extensive analyses of the bioactive chemicals in Carica papaya seeds and their modes of action are required to present a full picture

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: This study focused on the in vitro antibacterial efficacy of papaya seed ethanolic and aqueous extracts against Salmonella spp. and Candida albicans.
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Key Findings & Data:Results: The study found that the extracts worked better against Salmonella spp than Candida albicans, however, ethanol extract was stronger against the isolates with inhibition zone diameter (IZD) ranging from 10 mm to 32 mm, compared to the aqueous extract which only had 4 mm to 9 mm zones at certain concentrations.
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Conclusion & Impact:As a result, extensive analyses of the bioactive chemicals in Carica papaya seeds and their modes of action are required to present a full picture
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Power of Papaya Seeds · Antimicrobial Effects · plant medicine

Abstract

Objective: This study focused on the in vitro antibacterial efficacy of papaya seed ethanolic and aqueous extracts against Salmonella spp. and Candida albicans. Material-Method: Dry seeds of Carica papaya were extracted with ethanol and hot water and tested for antimicrobial activity against Salmonella spp and Candida albicans using agar well diffusion method on Muller Hilton agar. Results: The study found that the extracts worked better against Salmonella spp than Candida albicans, however, ethanol extract was stronger against the isolates with inhibition zone diameter (IZD) ranging from 10 mm to 32 mm, compared to the aqueous extract which only had 4 mm to 9 mm zones at certain concentrations. Conclusion: The activity of Carica papaya seed extracts demonstrates that the seeds are as significant as other parts of the plant and provides a scientific basis for the seeds' use in the treatment of many ailments in the local community. The extracts were more effective against Salmonella spp., with the ethanol extract having the highest antibacterial activity, indicating that the components of papaya seeds are more soluble in organic solvents and had stronger bactericidal characteristics. As a result, extensive analyses of the bioactive chemicals in Carica papaya seeds and their modes of action are required to present a full picture

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Cite This Article

OBOH, E., ASHEFO, D., OLEGHE, P., OJEİ, O. (2023). Investigating the Astonishing Antimicrobial Potential of Papaya seeds against Salmonella spp and Candida albicans. International Journal of Traditional and Complementary Medicine Research, Cilt: 4 Sayı: 1, 26–30. https://ajindex.com/articles/906859

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References (12)

  1. Bushra I, Fozia Abdul W, Ali R, Ullah Hussain, Iqbal Hamid, Almas M, Ahmad A. Antimicrobial activity of Malvaneglecta and Nasturtium microphyllum. Int. J. Res. in Ayurveda Pharm. 2012;3:808-810
  2. Dagne E, Dobo B, Bedewi Z. Antibacterial Activity of papaya (Carica papaya) leaf and seed extracts against some selected Gram-positive and Gram-negative bacteria. Pharma. J. 2021; 13(6): 1727-1733
  3. Alabi OA, Haruna MT, Anokwuru CP, Jegede T, Abia H, Okegbe, Esan E. Comparative studies on antimicrobial properties of extracts of fresh and dried leaves of Carica papaya (L) on clinical bacterial and fungal isolates. Pelagia Research Library. 2012;3(5):3107-3114
  4. Aravind G, Debjit B, Duraivel S, and Harish G. Traditional and medicinal uses of Carica papaya. J. Med Plants Studies. 2013;1(1):7-15
  5. Kovendan K, Murugan K, Panneerselvam C, Aarthi N, Kumar P M, Subramaniam J, and Amerasan D. Antimalarial activity of Carica papaya (Family: Caricaceae ) leaf extract against Plasmodium falciparum. Asian Pac J. Trop. Dis. 2012;2,S306–S311
  6. Udegbunam R. I, Ode J O, Ekwere M R. Anti-fertility effects of Carica papaya ( Pawpaw ) Linn. Methanol root extract in male Wistar rats. Arabian J. Chem. 2014;
  7. Devi S V, Prakash N K U A. Study on phytochemistry, antimicrobial antifungal and antioxidant properties of male flower of Carica Papaya L. Int. J. App. Bio. 2011;2(1), 20–23
  8. Anibijuwon I I, Udeze A O. Antimicrobial Activity of Carica papaya (Pawpaw Leaf) on some pathogenic organisms of clinical origin from South-Western Nigeria. Ethnobotanical Leaflets. 2009; 13, 850–64
  9. Nirosha N Mangalanayi R. Antibacterial activity of leaves and stem extract of Carica papaya L. Int. J. Adv. Phar. Bio. Chem. 2013;2(3).473-476
  10. Adeneye A A, Olagunju J A, Banjo A F, Abdul S F, Sanusi O A, Sanni O O, Shonoiki O E. The aqueous seed extract of Carica papaya Linn. Prevents carbon tetrachloride induced hepatotoxicity in rats. Int. J. Appl. Res.Nat. Prod. 2009;2(2), 19-32 11. Tona L, Kambu K, Ngimbi N, Cimanga K, Vlietinck A J. Antiamoebic and phytochemical screening of some Congolese medicinal plants. J. Ethnopharm. 1998;61,57–65
  11. Otsuki N, Dang N H, Kumagai E, Kondo A, Iwata S, Morimoto C. Aqueous extract of Carica papaya leaves exhibits anti-tumor activity and immunomodulatory effects. J. Ethnopharm. 2010;127,760–767
  12. Jyotsna, K. P., Yashab, K., Priyanka, P. and Harison, M. Antibacterial activity of seed and leaf ext