AI Summary & Key Takeaways
AI InsightConclusion: As the mitotic activity rate of nasal polyps increases, both the volume of the polyps and the computed tomography scores increase as a result of the blockage of the sinus ostiums by the increased polyp volume.
📌 3 Key Takeaways
Abstract
Objectives: The disease extention in nasal polyps was compared by using the mitotic activity rates and the computed tomography scores. Patients and Methods: This study was conducted on 19 nasal polyposis patients 8 males, 11 females; mean age 40.0±13.7 years; range 20 to 63 years . The preoperative computed tomography records of the patients were evaluated according to the Lund-Mackay grading system. The polyp tissues of the same patients were stained with the Ki-67 antigen for immunohistochemical evaluation. The correlation between the radiologic results and the Ki-67 values was compared by means of the Spearman’s correlation test. Results: The mean computed tomography score was observed as 14.3±4.7 range 7-24 . The mean Ki-67 score resulting from the immunohistochemical staining was calculated as 24.3±18.5 range %3.3-73.5 . A significant correlation was determined between the Ki-67 values and the computed tomography scores. “Spearman’s” correlation factor: 0.677; p<0.001 . Conclusion: As the mitotic activity rate of nasal polyps increases, both the volume of the polyps and the computed tomography scores increase as a result of the blockage of the sinus ostiums by the increased polyp volume.
Özet
Amaç: Nazal poliplerde, hastalığın yaygınlığı mitotik aktivite oranları ve bilgisayarlı tomografi skorları kullanılarak karşılaştırıldı.Hastalar ve Yöntemler: Çalışmaya 19 nazal polipozis hastası 8 erkek, 11 kadın; ort. yaş 40.0±13.7 yıl; dağılım 20-63 yıl dahil edildi. Hastaların ameliyat öncesi bilgisayarlı tomografi kayıtları LundMackay evreleme sistemine göre değerlendirildi. Aynı hastaların polip dokuları immünohistokimyasal değerlendirme amacıyla Ki-67 antijeni ile boyandı. Radyolojik sonuçlarla Ki-67 boyanma yüzdeleri arasındaki ilişki Spearman korelasyon testi ile karşılaştırıldı.Bulgular: Hastaların bilgisayarlı tomografi skor ortalaması 14.3±4.7 olarak gözlendi. İmmünohistokimyasal boyama sonucunda elde edilen Ki-67 skor ortalaması 24.3±18.5 dağılım %3.373.5 olarak hesaplandı. Ki-67 değerleri ile bilgisayarlı tomografi skorları arasında istatistiksel olarak ileri düzeyde anlamlı ilişki saptandı Spearman korelasyon katsayısı: 0.677; p