Journals / Celal Bayar Üniversitesi Fen Bilimleri Dergisi / 2023 / Cilt: 19 - Sayı: 1

A Study on Total Phenolic and Flavonoid Content, Antioxidant, Toxicity, and Antihelmintic Activities of Methanol Extracts of Crocus cancellatus subsp. lycuis

Pages
73–78
Publication Date
2023-03-28
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

According to these results, Crocus cancellatus subsp. lycuis may be paid attention as a good source for the pharmaceutical and food industries.

📌 3 Key Takeaways

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Objective & Hypothesis:The present study was planned to assess total phenolic and flavonoid content and some biological properties (antioxidant, toxicity, and antihelmintic) of the methanol extracts of Crocus cancellatus subsp. lycuis from Muğla province (Turkey) for the first time.
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Key Findings & Data:Total phenolic (2.08±0.06 mg GAE/g) and total flavonoid (3.63±0.09 mg QE/g) contents of the aerial part extract were higher than the bulb extract.
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Conclusion & Impact:According to these results, Crocus cancellatus subsp. lycuis may be paid attention as a good source for the pharmaceutical and food industries.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Anthelmintic · Antioxidant · Brine shrimp

Abstract

The present study was planned to assess total phenolic and flavonoid content and some biological properties (antioxidant, toxicity, and antihelmintic) of the methanol extracts of Crocus cancellatus subsp. lycuis from Muğla province (Turkey) for the first time. Total phenolic (2.08±0.06 mg GAE/g) and total flavonoid (3.63±0.09 mg QE/g) contents of the aerial part extract were higher than the bulb extract. The aerial part extract (IC50 value: 0,86±0,03 mg/mL, IC50 value: 0,26±0,003 mg/mL, 0,77±0,007 mg TE/g, and 5,92±0,30 mg TE/g, respectively) was determined to exhibit the higher activity than that of bulb parts extract in the assays shortly named as DPPH, ABTS, FRAP and CUPRAC carried out to examine the antioxidant activities of the extracts. Both extracts were observed to be effective on brine shrimp and to have anthelmintic activity. According to these results, Crocus cancellatus subsp. lycuis may be paid attention as a good source for the pharmaceutical and food industries.

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Cite This Article

ALPER, M., ATAY, M. Ö., CEYLAN, O., MAMMADOV, R. (2023). A Study on Total Phenolic and Flavonoid Content, Antioxidant, Toxicity, and Antihelmintic Activities of Methanol Extracts of Crocus cancellatus subsp. lycuis. Celal Bayar Üniversitesi Fen Bilimleri Dergisi, Cilt: 19 - Sayı: 1, 73–78. https://ajindex.com/articles/891709

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References (2)

  1. 1]. Rehman, M. U., Wali, A. F., Ahmad, A., Shakeel, S., Rasool, S., Ali, R.,. & Khan, R. (2019). Neuroprotective strategies for neurological disorders by natural products: an update. Current Neuropharmacology,17(3),247-267. [2]. Bernardini, S., Tiezzi, A., Laghezza Masci, V., & Ovidi, E. (2018). Natural products for human health: an historical overview of the drug discovery approaches. Natural product research, 32(16), 1926-1950. [3]. Raina, H., Soni, G., Jauhari, N., Sharma, N., & Bharadvaja, N. (2014). Phytochemical importance of medicinal plants as potential sources of anticancer agents. Turkish Journal of Botany, 38(6), 1027-1035. [4]. Alamgir, A.N.M. (2018). Introduction. In: Therapeutic Use of Medicinal Plants and their Extracts: Volume 2. Progress in Drug Research, vol 74. Springer, Cham. https://doi.org/10.1007/978-3-319-92387-1_1 [5]. Che, C. T., & Zhang, H. (2019). Plant Natural Products for Human Health. International journal of molecular sciences, 20(4), 830.https://doi.org/10.3390/ijms20040830 [6]. Loizzo, O., Kovalyov, V., Goryacha, O., Ivanauskas, L., & Georgiyants, V. (2019). Biologically active compounds and pharmacological activities of species of the genus Crocus: A review. Phytochemistry,162,56-89. [7]. Mohtashami, L., Amiri, M. S., Ramezani, M., Emami, S. A., & Simal-Gandara, J. (2021). The genus Crocus L.: A review of ethnobotanical uses, phytochemistry and pharmacology. Industrial Cops and Products, 171, 113923. [8]. P.H. Davis, R. Mill, K. Tan Flora of Turkey and the East Aegean Islands (Supplement I), vol. 10, Edinburgh University Press,
  2. Edinburgh (1988) 278pp [9]. Verma, S. K., Das, A. K., Cingoz, G. S., Uslu, E., & Gurel, E. (2016). Influence of nutrient media on callus induction, somatic embryogenesis and plant regeneration in selected Turkish crocus species. Biotechnology Reports, 10, 66-74. [10]. Turan, M., Mammadov, R. 2018. “Antioxidant, Antimicrobial, Cytotoxic, Larvicidal and Anthelmintic Activities and Phenolic Contents of Cyclamen alpinum”, Pharmacology & Pharmacy, 9, 100-116. [11]. Singleton, V.L., Rossi, J.A. 1965. ‘’Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents’’, American Journal of Enology and Viticulture, 16(3), 144-158. [12]. Aryal, S., Baniya, M. K., Danekhu, K., Kunwar, P., Gurung, R., Koirala, N. 2019. ‘’Total phenolic content, flavonoid content and antioxidant potential of wild vegetables from Western Nepal’’, Plants, 8(4), 96. [13]. Re, R., Pellegrini, N., Proteggente, A