SavedAdd your journal

Journals / Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi / 2023 / Cilt: 13 - Sayı: 1

Investigation of Some Biological Activities of Ajuga chamaepitys subsp. chia

Atiye Nur SAVAŞ
Nurcihan HACIOĞLU
Neslihan DEMİR
Pages
162–169
Publication Date
2023-03-01
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The highest antioxidant activity was obtained from plants ethyl acetate extract.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Ajuga L., which is an Eastern Mediterranean element, is popularly known as ground pine, dwarf grass, ground cypress, bitter gourd, wormwood, yeast grass (mayasılotu in Turkish) (Zeybek and Zeybek, 1994).
📊
Key Findings & Data:Crystal violet binding assay were used to determinate antibiofilm activities of extracts against test microorganisms (4 Gram negative, 3 Gram positive and 1yeast).
💡
Conclusion & Impact:The highest antioxidant activity was obtained from plants ethyl acetate extract.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Ajuga chamaepitys subsp. chia · antibiofilm · time-kill assay

Abstract

Ajuga L., which is an Eastern Mediterranean element, is popularly known as ground pine, dwarf grass, ground cypress, bitter gourd, wormwood, yeast grass (mayasılotu in Turkish) (Zeybek and Zeybek, 1994). Ajuga chamaepitys L. Schreb species has been used since the Middle Ages as a diuretic, antidote for poisonous animal stings, and as an invigorating, wound-healing and diaphoretic plant. This study evaluated antibiofilm, time-kill potential and antioxidant activity of four extracts of A. chamaepitys subsp. chia (Schreb.) Arcang. Crystal violet binding assay were used to determinate antibiofilm activities of extracts against test microorganisms (4 Gram negative, 3 Gram positive and 1yeast). Antioxidant activity was evaluated by using 2,2-diphenyl1-picrylhydrazyl and reducing antioxidant capacity methods. The highest antibiofilm activity was obtained in acetone extract against P. aeruginosa ATCC 27853 and S. aureus ATCC 6538P bacteria. In the time-dependent killing test of plant extracts, microbicidal effect was obtained after 24 hours. The highest antioxidant activity was obtained from plants ethyl acetate extract.

🔖

Cite This Article

SAVAŞ, A. N., HACIOĞLU, N., DEMİR, N. (2023). Investigation of Some Biological Activities of Ajuga chamaepitys subsp. chia. Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi, Cilt: 13 - Sayı: 1, 162–169. https://ajindex.com/articles/886397

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (9)

  1. Apak R, Güçlü K, Özyürek M, Karademir SE, Altun M, (2005). Total Antioxidant Capacity Assay of Human Serum Using Copper(II)-Neocuproine as Chromogenic Oxidant: The CUPRAC Method. Free Radical Research, 39: 949-961. Blois MS, (1958). Antiontioxidant Determinations by the Use of a Stable Free Radical. Nature, 181: 1199–1200.
  2. Aumeeruddy-Elalfi Z, Gurib-Fakim A, Mahomoodally MF, (2016).
  3. Chemical Composition, Antimicrobial and Antibiotic Potentiating Activity of Essential Oils from 10 Tropical Medicinal Plants from Mauritius. Journal of Herbal Medicine, 6(2): 88–95.
  4. Bakari S, Daoud A, Felhi S, Smaoui S, Gharsallah N, Kadri A,(2016).
  5. Proximate Analysis, Mineral Composition, Phytochemical Contents, Antioxidant and Antimicrobial Activities and GC-MS Investigation of Various Solvent Extracts of Cactus cladode. Food Science and Technology, 37(2): 286-293. Baytop T, (1984). Therapy with Medicinal Plants in Turkey. Istanbul University Press,
  6. Istanbul-Turkey. Boakye YD, Agyare C. Andreas H, (2016). Anti-infective Properties and Time-kill Kinetics of Phyllanthus muellerianus and Its Major Constituent, Geraniin. Medicinal Chemistry, 6(2): 95–104.
  7. Chen H, Tan RX, Liu ZL, Zhang Y, Yang L, (1996). Antibacterial Neoclerodane Diterpenoids from Ajuga lupulina. Journal of Natural Products, 59: 668-670.
  8. Chenni A, Yahia DA, Boukortt FO, Prost J, Lacaille-Dubois MA, Bouchenak M, (2007). Effect of Aqueous Extract of Ajuga iva Supplementation on Plasma Lipid Profile and Tissue Antioxidant Status in Rats Fed a High-cholesterol Diet. Journal of Ethnopharmacolgy, 109: 207-213.
  9. Coll J, Tandrón YA, (2008). Neo-clerodane Diterpenoids from Ajuga: Structural Elucidation and Biological activity. Phytochemistry Review, 7: 25- 49. CLSI, (2006). Clinical and Laboratory Standarts Institute. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically; Approved Standard-Seventh Edition. M07- A7, Villanova, PA, USA. Davis PH, (1982). Flora of Turkey and the East Aegean Islands Vol. 7. Edinburgh University Press, Edinburgh. Duran Ö, (2015). Çay Olarak Tüketilen Lamiaceae Familyasının Antimutajenik, Antiproliferatif, Antikaryojenik, Antibiyofilm ve Hemostatik Aktivitelerinin İncelenmesi. Muğla Sıtkı Koçman University Institute of Natural and Applied Sciences, Master Thesis (Published). Jakovljević DZ, Vasić SM, Stanković MS, Čomić LR, Topuzović MD, (2015). Secondary Metabolite Content and In vitro Biological Effects of Ajuga chamaepitys (L.) schreb. subsp. chamaepitys.