Journals / Journal of Contemporary Medicine / 2022 / Cilt: 12 - Sayı: 6

Multisystem inflammatory syndrome in a male adolescent after his second Pfizer-BioNTech COVID-19 vaccine: a report from Turkey

Bir erkek ergende ikinci doz Pfizer-BioNTech COVID-19 aşısı sonrası multisistem inflamatuar sendrom: Türkiye'den bir rapor

Pages
1030–1032
Publication Date
2022-11-30
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We present details on a 15-year-old previously healthy Turkish male adolescent who fulfilled the diagnostic criteria for MIS-C after the Pfizer-BioNTech vaccine.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to spread rapidly through human populations, presenting across a continuum of severity from a symptomatic carriage to multi-organ failure and death.
📊
Key Findings & Data:Multisystem inflammatory syndrome in children (MIS-C) is a new phenomenon reported worldwide with temporal association with SARS-CoV-2.
💡
Conclusion & Impact:We present details on a 15-year-old previously healthy Turkish male adolescent who fulfilled the diagnostic criteria for MIS-C after the Pfizer-BioNTech vaccine.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Adolesan · covid-19 · multisistem inflamatuar sendrom

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to spread rapidly through human populations, presenting across a continuum of severity from a symptomatic carriage to multi-organ failure and death. Multisystem inflammatory syndrome in children (MIS-C) is a new phenomenon reported worldwide with temporal association with SARS-CoV-2. Multisystem inflammatory syndrome in children is a complication of the SARS-CoV-2 infection, while myocarditis is a rare adverse effect to messenger ribonucleic acid (mRNA) SARS-CoV-2 vaccines, especially in males aged 12–17 years . On the other hand, postimmunization myocarditis is a known rare adverse event after other vaccinations, such as smallpox . Today, rare cases of MIS-C and myocarditis after mRNA SARS-CoV-2 vaccinations have been reported in children or adolescents . We present details on a 15-year-old previously healthy Turkish male adolescent who fulfilled the diagnostic criteria for MIS-C after the Pfizer-BioNTech vaccine.

Özet

Koronavirüs 2 (SARS-CoV-2), semptomatik bir taşıyıcılıktan çoklu organ yetmezliğine ve mortaliteye neden olarak insanlar arasında hızla yayılmaya devam ediyor. Çocuklarda multisistem inflamatuar sendrom (MIS-C), SARS-CoV-2 ile giderek artan oranda dünya çapında bildirilen yeni bir fenomendir. Çocuklarda multisistem inflamatuar sendrom, SARS-CoV-2 enfeksiyonunun bir komplikasyonu iken miyokardit, haberci ribonükleik asit (mRNA) SARS-CoV-2 aşılarının, özellikle 12-17 yaş arası erkeklerde nadir görülen bir yan etkisidir. Diğer taraftan, bağışıklama sonrası miyokardit, çiçek hastalığı gibi diğer aşılardan sonra bilinen nadir bir advers olaydır. Günümüzde çocuklarda veya adolesanlarda mRNA SARS-CoV-2 aşıları sonrası nadir olarak MIS-C ve miyokardit vakaları bildirilmiştir. Pfizer-BioNTech aşısı sonrası MIS-C tanı kriterlerini karşılayan, daha önce sağlıklı olan 15 yaşında bir Türk erkek Adolesanın klinik bulgularını sunuyoruz.

🔖

Cite This Article

ALP, H., DOĞAN, M. T. (2022). Multisystem inflammatory syndrome in a male adolescent after his second Pfizer-BioNTech COVID-19 vaccine: a report from Turkey. Journal of Contemporary Medicine, Cilt: 12 - Sayı: 6, 1030–1032. https://ajindex.com/articles/869189

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. Yasuhara J, Watanabe K, Takagi H, Sumitomo N, Kuno T. COVID-19 and multisystem inflammatory syndrome in children: A systematic review and meta-analysis. Pediatr Pulmonol 2021; 56: 837-48
  2. Vogel TP, Top KA, Karatzios C, et al. Multisystem inflammatory syndrome in children and adults (MIS-C/A): case definition &guidelines for data collection, analysis, and presentation of immunization safety data. Vaccine 2021; 39: 3037-49
  3. Jain SS, Steele JM, Fonseca B, et al. COVID-19 vaccination-associated myocarditis in adolescents. Pediatrics 2021; 148: e2021053427
  4. Marshall M, Ferguson ID, Lewis P, et al. Symptomatic Acute Myocarditis in 7 Adolescents After Pfizer-BioNTech COVID 19 Vaccination. Pediatrics 2021; 148: e2021052478
  5. Halsell JS, Riddle JR, Atwood JE, et al; Department of Defense Smallpox Vaccination Clinical Evaluation Team. Myopericarditis following smallpox vaccination among vaccinia-naive US military personnel. JAMA 2003; 289: 3283–9
  6. Chai Q, Nygaard U, Schmidt RC, Zaremba T, Møller AM, Thorvig CM. Multisystem inflammatory syndrome in a male adolescent after his second Pfizer-BioNTech COVID-19 vaccine. Acta Paediatr 2022; 111: 125-7
  7. Buchhorn R, Meyer C, Schulze-Forster K, Junker J, Heidecke H. Autoantibody Release in Children after Corona Virus mRNA Vaccination: A Risk Factor of Multisystem Inflammatory Syndrome? Vaccines (Basel). 2021; 9: 1353
  8. Nune A, Iyengar KP, Goddard C, Ahmed AE. Multisystem inflammatory syndrome in an adult following the SARS-CoV-2 vaccine (MIS-V). BMJ Case Rep 2021; 14(7): e243888
  9. Pfizer-BioNTech. Full emergency use authorization (EUA) prescribing information. Available at: http://labeling.pfizer.com/ShowLabeling.aspx?id=14471&format= pdf&#page=13. Accessed May 15, 2021
  10. Liu W, Liu Z, Li YC. COVID-19-related myocarditis and cholinergic anti-inflammatory pathways. Hell J Cardiol Ep 2021, 62, 265–9.