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Journals / Journal of Contemporary Medicine / 2022 / Cilt: 12 - Sayı: 6

Oxidative Stress Index and Vitamin C in The Diagnosis of Fibromyalgia Syndrome

Fibromiyalji Sendromu Tanısında Oksidatif Stres İndeksi ve C Vitamini

Muzaffer KATAR
Köksal DEVECİ
Hülya DEVECİ
Pages
1007–1012
Publication Date
2022-11-30
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was a moderate positive and significant relationship between the tender points and FIQ, (r = 0.505; p

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Still there is no any specific laboratory marker for diagnosis of FMS and it mainly depends on clinical examination.
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Key Findings & Data:Material and Method: 53 female patients and 35 healthy female controls were enrolled to our cross-sectional study.
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Conclusion & Impact:There was a moderate positive and significant relationship between the tender points and FIQ, (r = 0.505; p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Fibromiyalji Sendromu · TAC · OSI

Abstract

Aim: Still there is no any specific laboratory marker for diagnosis of FMS and it mainly depends on clinical examination. So that we aimed to evaluate whether serum Vitamin C levels and oxidative stress index (OSI) can be used in the diagnosis of Fibromyalgia Syndrome (FMS). Material and Method: 53 female patients and 35 healthy female controls were enrolled to our cross-sectional study. VAS, BDI and FIQ were applied to the patients. Vitamin C levels were measured by HPLC. Total Antioxidant Capacity (TAC) and Total Oxidant Status (TOS) levels were determined by Spectrophotometric Assay method. Results: While vitamin C and TAC levels of FMS patients were significantly lower than those of the controls, OSI was significantly higher in patients (p= 0.004, p= 0.009 and p= 0.048, respectively). There was a moderate positive and significant relationship between the tender points and FIQ, (r = 0.505; p

Özet

Amaç: FMS tanısı için spesifik bir laboratuvar belirteci yoktur ve esas olarak klinik muayeneye bağlıdır. Serum C vitamini düzeylerinin ve oksidatif stres indeksinin (OSI) Fibromiyalji Sendromu (FMS) tanısında kullanılıp kullanılamayacağını değerlendirmeyi amaçladık. Gereç ve Yöntem: Kesitsel çalışmamıza 53 kadın hasta ve 35 sağlıklı kadın kontrol dahil edildi. Hastalara VAS, BDI ve FIQ uygulandı. C vitamini seviyeleri HPLC ile ölçüldü. Toplam Antioksidan Kapasitesi (TAC) ve Toplam Oksidan Durumu (TOS) seviyeleri Spektrofotometrik yöntemle belirlendi. Bulgular: FMS hastalarının vitamin C ve TAC düzeyleri kontrollere göre anlamlı olarak düşük iken, hastalarda OSİ anlamlı olarak daha yüksekti (sırasıyla p= 0,004, p= 0,009 ve p= 0,048). Hassas noktalar ile FIQ arasında orta düzeyde pozitif ve anlamlı bir ilişki vardı (r = 0,505; p

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Cite This Article

KATAR, M., DEVECİ, K., DEVECİ, H. (2022). Oxidative Stress Index and Vitamin C in The Diagnosis of Fibromyalgia Syndrome. Journal of Contemporary Medicine, Cilt: 12 - Sayı: 6, 1007–1012. https://ajindex.com/articles/869187

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