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Journals / Mustafa Kemal Üniversitesi Tıp Dergisi / 2022 / Cilt: 13 - Sayı: 47

Effects of Achillea millefolium extract on spontaneous and oxytocin-induced isolated rat uterine contractions

Achillea millefolium ekstraktının spontan ve oksitosin ile indüklenen izole sıçan uterus kasılmaları üzerine etkileri

Ali EKER
Faik ÖZDENGÜL
Melda Pelin YARGIÇ
Aysu ŞEN
Pages
290–295
Publication Date
2022-12-15
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The differences at the level of p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Achillea millefolium (AM) is widely used in traditional medicine in a wide geography due to its effects on the female reproductive system.
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Key Findings & Data:Method: Myometrial strips were obtained from 32 adult Wistar Albino rats.
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Conclusion & Impact:The differences at the level of p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Achillea millefolium · oksitosin · oksitosinle indüklenmiş kasılma

Abstract

Objective: Achillea millefolium (AM) is widely used in traditional medicine in a wide geography due to its effects on the female reproductive system. However, its effect on uterine smooth muscle contractions is unknown. Our study aims to investigate the effects of AM on spontaneous and oxytocin-induced isolated rat uterine contractions. Method: Myometrial strips were obtained from 32 adult Wistar Albino rats. Contraction amplitudes and frequencies were recorded by isolated tissue bath system after either of the following: administration of only Krebs-Hanseleit (KBH) solution, administration of Achillea millefolium extract (AME); administration of KBH or AME after inducing contractions with oxytocin. The differences at the level of p

Özet

Amaç: Achillea millefolium (AM), kadın üreme sistemi üzerindeki etkileri nedeniyle geniş bir coğrafyada geleneksel tıpta yaygın olarak kullanılmaktadır. Ancak uterus düz kas kasılmaları üzerindeki etkisi bilinmemektedir. Çalışmamız AM’nin spontan ve oksitosin kaynaklı izole sıçan uterus kasılmaları üzerindeki etkilerini araştırmayı amaçlamaktadır. Yöntem: Myometrial şeritler 32 yetişkin Wistar Albino sıçanından elde edildi. Kasılma genlikleri ve frekansları, belirtilen uygulamaların ardından izole organ banyosu sisteminde kaydedildi: Yalnızca Krebs-Hanseleit (KBH) çözeltisinin uygulanması, Achillea millefolium ekstraktının (AME) uygulanması; oksitosin ile kasılmaları indükledikten sonra KBH veya AME uygulaması. p

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Cite This Article

EKER, A., ÖZDENGÜL, F., YARGIÇ, M. P., ŞEN, A. (2022). Effects of Achillea millefolium extract on spontaneous and oxytocin-induced isolated rat uterine contractions. Mustafa Kemal Üniversitesi Tıp Dergisi, Cilt: 13 - Sayı: 47, 290–295. https://ajindex.com/articles/862090

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