John's Wort and evening primrose oils on the JAK-STAT signaling pathway.
📌 3 Key Takeaways
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Objective & Hypothesis:Objective: Multiple Sclerosis is an autoimmune demyelinating disease that progresses with inflammatory infiltrates in the central nervous system.
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Key Findings & Data:Dysregulation of the JAK-STAT signaling pathway plays an important role in the pathogenesis of experimental autoimmune encephalomyelitis-induced Multiple Sclerosis models.
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Conclusion & Impact:John's Wort and evening primrose oils on the JAK-STAT signaling pathway.
Objective: Multiple Sclerosis is an autoimmune demyelinating disease that progresses with inflammatory infiltrates in the central nervous system. Dysregulation of the JAK-STAT signaling pathway plays an important role in the pathogenesis of experimental autoimmune encephalomyelitis-induced Multiple Sclerosis models. The aim of this study was to reveal the therapeutic effects of the consumption of St. John's Wort and evening primrose oils on the JAK-STAT signaling pathway.
Özet
Amaç: Multipl Skleroz, merkezi sinir sisteminde inflamatuar infiltrasyonlarla ilerleyen otoimmün demiyelinizan bir hastalıktır. JAK-STAT sinyal yolunun düzensizliği, otoimmün ensefalomiyelit ile indüklenmiş Multipl Skleroz modellerinin patogenezinde önemli bir rol oynar. Bu çalışmanın amacı, sarı kantaron ve çuha çiçeği yağlarının tüketiminin, JAK-STAT sinyal yolu üzerindeki terapötik etkilerini ortaya çıkarmaktır.
BULUT, H., TELOĞLU, E. Ş., ŞENTÜRK, H., ÜSTÜNOVA, S., GÜLEKEN, Z., SELEK, Ş. (2022). The Effect of Evening Primrose and St. John's Wort Oils on Jak/STAT Signaling Pathways in Mice with Multiple Sclerosis Modeled. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi, Cilt: 24 - Sayı: 2, 225–235. https://ajindex.com/articles/860928
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