Journals / Cukurova Medical Journal / 2022 / Cilt: 47 - Sayı: 4

Relationship between theory of mind and metabolic parameters and functioning in patients with bipolar I disorder

Bipolar I bozukluk tanılı hastalarda zihin kuramının, metabolik parametreler ve işlevsellik ile ilişkisi

Pages
1610–1619
Publication Date
2022-12-28
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Metabolic alteration and theory of mind impairment should be potential treatment target for BD

📌 3 Key Takeaways

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Objective & Hypothesis:Purpose: We aimed to investigate the relationship theory of mind abilities with functionality and metabolic alteration in patients with bipolar disorder-1 (BD-1) during the remission period.
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Key Findings & Data:Materials and Methods: This cross-sectional study is consisted of 68 patients with bipolar disorder-1 and 45 healthy controls.
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Conclusion & Impact:Metabolic alteration and theory of mind impairment should be potential treatment target for BD
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Zihin kuramı · bipolar bozukluk · metabolik disfonksiyon

Abstract

Purpose: We aimed to investigate the relationship theory of mind abilities with functionality and metabolic alteration in patients with bipolar disorder-1 (BD-1) during the remission period. Materials and Methods: This cross-sectional study is consisted of 68 patients with bipolar disorder-1 and 45 healthy controls. Sociodemographic form, Reading the Mind in the Eyes Test (RMET), Bipolar Disorder Functioning Questionnaire (BDFQ) were administered to the participants. Body mass index (BMI), waist circumference (WC), fasting plasma glucose (FG), high density lipoprotein cholesterol (HDL), low density lipoprotein cholesterol (LDL), total cholesterol (TC), triglyceride (TG) levels were recorded. Results: There were significant differences between the patient group and healthy control group in terms of WC, BMI, HDL, LDL, TG. The results of independent samples t-test indicated a statistically significant difference in RMET score between the two groups with control group significantly higher than patient group. Conclusion: Patients with BD-1 during the remission period have lower performance on theory of mind abilities and more alteration in metabolic parameters than healthy controls. Metabolic alteration and theory of mind impairment should be potential treatment target for BD

Özet

Amaç: Bu çalışmada bipolar bozukluk-1 (BB-1) tanılı hastaların remisyon dönemlerindeki zihin kuramı becerileri ile, işlevsellik ve metabolik değişimleri arasındaki ilişkiyi araştırmayı amaçladık. Gereç ve Yöntem: Bu kesitsel çalışma, remisyonda BB-1 tanılı 68 hasta ve 45 sağlıklı kontrolden oluşmaktadır. Katılımcılara sosyodemografik form, Gözlerden Zihin Okuma Testi, Bipolar Bozukluk İşlevsellik Anketi uygulandı. Katılımcıların beden kitle indeksi (BKİ), bel çevresi (BÇ), açlık plazma glukozu (PG), yüksek yoğunluklu lipoprotein kolesterol (HDL), düşük yoğunluklu lipoprotein kolesterol (LDL), toplam kolesterol, trigliserit (TG) seviyeleri kaydedildi. Bulgular: Hasta grubu ile sağlıklı kontrol grubu arasında BÇ, BKİ, HDL, LDL, TG düzeyleri açısından anlamlı farklılıklar vardı. Bağımsız örnekler t-testi sonuçlarına göre kontrol grubunda hasta grubuna göre Gözlerden Zihin Okuma Testi’nde istatistiki olarak anlamlı daha yüksek skorlar elde edilmiştir. Sonuç: Remisyon döneminde BB-1 tanılı hastalar, sağlıklı kontrollere göre zihin kuramı becerilerinde daha düşük performansa ve metabolik parametrelerde daha fazla değişikliğe sahiptir. Metabolik değişiklik ve zihin bozukluğu teorisi, BD için potansiyel tedavi hedefi olmalıdır.

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Cite This Article

KULACAOĞLU, F., ÜNVER, H., YILDIRIM, Y. E., ERZİN, G. (2022). Relationship between theory of mind and metabolic parameters and functioning in patients with bipolar I disorder. Cukurova Medical Journal, Cilt: 47 - Sayı: 4, 1610–1619. https://ajindex.com/articles/858416

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References (14)

  1. Vieta E, de Arce R, Jiménez-Arriero MA, Rodriguez A, Balanzá V, Cobaleda S. Detection of subclinical depression in bipolar disorder: a cross-sectional, 4-month prospective follow-up study at community mental health services (SIN-DEPRES). J Clin Psychiatry. 2010;71:4291
  2. Sanchez-Moreno J, Martinez-Aran A, Tabarés-Seisdedos R, Torrent C, Vieta E, Ayuso-Mateos JL. Functioning and disability in bipolar disorder: an extensive review. Psychother Psychosom. 2009;78:285–97
  3. Kurtz MM, Gerraty RT. A meta-analytic investigation of neurocognitive deficits in bipolar illness: profile and effects of clinical state. Neuropsychology. 2009;23:551
  4. Cullen B, Ward J, Graham NA, Deary IJ, Pell JP, Smith DJ, et al. Prevalence and correlates of cognitive impairment in euthymic adults with bipolar disorder: a systematic review. J Affect Disord. 2016;205:165–81
  5. Fiske ST, Taylor SE. Social cognition. Mcgraw-Hill Book Company; 1991
  6. Green MF, Horan WP, Lee J. Social cognition in schizophrenia. Nat Rev Neurosci. 2015;16:620–31
  7. Green MF, Leitman DI. Social cognition in schizophrenia. Schizophr Bull. 2008;34:670–2
  8. Pinkham AE, Penn DL, Perkins DO, Lieberman J. Implications for the neural basis of social cognition for the study of schizophrenia. Am J Psychiatry. 2003;160(5):815–24
  9. Brüne M. Social cognition and psychopathology in an evolutionary perspective. Psychopathology. 2001;34:85–94
  10. Samamé C, Martino DJ, Strejilevich SA. Social cognition in euthymic bipolar disorder: Systematic review and meta-analytic approach. Acta Psychiatr Scand. 2012;125:266–80
  11. Samamé C, Martino DJ, Strejilevich SA. An individual task meta-analysis of social cognition in euthymic bipolar disorders. J Affect Disord. 2015;173:146–53
  12. Bora E, Bartholomeusz C, Pantelis C. Meta-analysis of Theory of Mind (ToM) impairment in bipolar disorder. Psychol Med. 2016;46:253–64. 13. van Neerven T, Bos DJ, van Haren NE. Deficiencies in Theory of Mind in patients with schizophrenia, bipolar disorder, and major depressive disorder: A systematic review of secondary literature. Neurosci Biobehav Rev. 2021;120:249–61
  13. Baron-Cohen S, Wheelwright S, Hill J, Raste Y, Plumb I. The “Reading the Mind in the Eyes” Test revised version: a study with normal adults, and adults with Asperger syndrome or high-functioning autism. J Child Psychol Psychiatry. 2001;42:241–51
  14. Ibanez A, Cetkovich M, Petroni A, Urquina H, Baez S, Gonzalez-Gadea ML, et al. The neural basis of decision-making and