SavedAdd your journal

Journals / OPUS Toplum Araştırmaları Dergisi / 1996 / Cilt: 1 - Sayı: 2

The Effectivity of Prosta Glandin Synthetase Inhibitors and Spasmolytics in Treatment of Renal Colic

Prostaglandin Sentetaz İnhibitörleri ile Spazmolitiklerin Renal Kolik Tedavisindeki Etkinlikleri

Orhan YALÇIN
Can BAYDİNÇ
Atilla SEMERCİÖZ
Ercan YENİ
Pages
17–19
Publication Date
1996-12-30
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In conclusion, we thought that NSAID can be the first preference for the treatment of renal colic.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Spasmolytics, narcotic analgesics, calcium antagonists and prostaglandin synthetase inhibitors (NSAI) are applied widely in treatment of renal colic.
📊
Key Findings & Data:We studied in two group and each group contained 20 patients.
💡
Conclusion & Impact:In conclusion, we thought that NSAID can be the first preference for the treatment of renal colic.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Renal kolik · prostaglandin sentetaz inhibitörleri · NSAI ilaçlar

Abstract

Spasmolytics, narcotic analgesics, calcium antagonists and prostaglandin synthetase inhibitors (NSAI) are applied widely in treatment of renal colic. Amoung these drugs, NSAI drugs are believed to be more effective and safe. In this trial, we purposed to compare NSAI and spasmolytic drugs as for their effects and side effects in the patients with renal colic. We studied in two group and each group contained 20 patients. In the first group we applied diclofenac sodium intramuscularely which is a NSAI drug and in the second group hyoscine N butylbromide was applied intramuscularely which is a spasmolytic drug. The results was noted after 15, 30, 45 and 60 minutes. We found no statistically significant difference between two groups for drug effectivities, but we found that there was a statistically significant difference in the side effects between the groups. In conclusion, we thought that NSAID can be the first preference for the treatment of renal colic.

Özet

Renal kolik tedavisinde spazmolitikler, narkotik analjezikler, kalsiyum antagonistleri ve prostaglandin sentetaz inhibitörleri olan nonsteroid antiinflamatuar analjezikler (NSAI) yaygın olarak kullanılmaktadır. Bunlardan NSAI ilaçlar etkili ve güvenilir olarak kabul edilmektedirler. Bu çalışmamızda NSAI analjezikler ile spazmolitik ilaçları renal kolikli hastalarda etkinlikleri ve yan etkileri yönünden karşılaştırmayı amaçladık. Bunun için 20’şer olguluk iki grup oluşturduk. Birinci gruba NSAI bir ilaç olan diklofenak sodyum (Dic. Na), ikinci gruba ise spazmolitik bir ilaç olan hyoscine N. bütil bromid (HNBB)'i intramusküler olarak uyguladık. Enjeksiyondan sonra 15 , 30 , 45 ve 60 inci dakikalardaki sonuçları not ettik. İki grup arasında ilaçların etkinlikleri yönünden istatistiksel olarak anlamlı fark olmamasına rağmen yan etkiler yönünden fark anlamlı idi. Buna göre; renal, üreteral kolikli hastaların tedavisinde NSAI’ların öncelikle tercih edilebilir olduğu sonucuna vardık.

🔖

Cite This Article

YALÇIN, O., BAYDİNÇ, C., SEMERCİÖZ, A., YENİ, E. (1996). The Effectivity of Prosta Glandin Synthetase Inhibitors and Spasmolytics in Treatment of Renal Colic. OPUS Toplum Araştırmaları Dergisi, Cilt: 1 - Sayı: 2, 17–19. https://ajindex.com/articles/856653

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (4)

  1. Nissen I, Birke H, Olsen JB et al. Treatment of ureteric colic. Intravenous versus rectaI administration of indomethacin. Br J Urol. 1990;65(6):576-579. doi: 10.1111/j.1464-410x.1990.tb14823.x Başar I, Bircan K, Taşar C, Ergen A, Çakmak F, Remzi D. Diclofenac sodium and spasmolytic drugs in treatment of ureteral colic. A comperative study. Int Urol Nephrol. 1991;23(3):227-230. doi: 10.1007/bf02550416 Edna TH, Heselberg F, Loe B. Indomethacin in the treatment of ureteral colic. J Urol. 1986;136(2):390-392. doi: 10.1016/s0022-5347(17)44877-4 Kantor TG. Use of diclofenac in analgesia. Am J Med. 1986;80(4B):64-69. doi: 10.1016/0002-9343(86)90083-5 Çıkılı N, ve ark. Üreteral kolik tedavisinde diclofenac sodyum kullanımı (70 olguluk bir klinik araştırma). Türk Üroloji Dergisi. 1988;14:409¬413. Sommer P, Kromann-Andersen B, Lendorf A, Lyngdorf P, Moller P. Analgesic effect and tolerance of voltaren and ketogen in acut renal and ureteric colic. Br J Urol. 1989;63(1):4-6. doi: 10.1111/j.1464-410x.1989.tb05112.x Khalifa MS, Sharkaw MA. Treatment of pain owing to acute ureteral obstruction with prostaglandin synthetase inhibitor. a prospective randomised study. J Urol. 1986;136(2):393-395. doi: 10.1016/s0022-5347(17)44878-6 Obrion WM. Advers reactions to nonsteroidal antiinfamator drugs. Am J Med. 1986; 80(4B):70-80. doi: 10.1016/0002-9343(86)90084-7
  2. Flannigan GM, Clifford RP, Carver RA, Yule AG, Madden NP, Towler JM. Indomethacin an alternative to pethidine in ureteric colic. Br J Urol. 1983;55(1):6-9. doi: 10.1111/j.1464-410x.1983.tb07069.x Lundstam SOA, Wahlander L, Kral JG. Treatment of ureteral colic by prostaglandin synthetase inhibition with diclofenac sodium. Curr Ther Res, 1987;28:355-358.
  3. Holmlund D, Sjodin JG. Treatment of ureteric colic with IV indomethacin. J Urol. 1978;120(6):676-677. doi: 10.1016/s0022-5347(17)57325-5 el-Sherif AE, Foda R, Norlen LJ, Yahia H. Treatment of renal colic by prostaglandin synthetase inhibitors and avofortan. Br J Urol. 1990;66(6):602-605. doi: 10.1111/j.1464-410x.1990.tb07190.x Lundstam SO, Leisssner KH, Wahlender LA, Kral JG. Prostaglandin synthetase inhibition with diclofenac sodium in teratment of renal colic. Comparison with use a narcotic analgesic. Lancet. 1982;1(8281):1096-1097. doi: 10.1016/s0140-6736(82)92278-4 Aydınlı I. Ağrının değerlendirilmesi. Ağrı serisi Hekimler Yayın Birliği. Medikomat Basım Yayın San. ve Tic. Ltd. Şti: Ankara; 1995:29-40.
  4. Sjodin JG, Holmlund D. Indomethacin by intravenous infusion in uret