SavedAdd your journal

Journals / OPUS Toplum Araştırmaları Dergisi / 1997 / Cilt: 2 - Sayı: 2

Gardner Syndrome: Case Report

Gardner Sendromu: Olgu Sunumu

Altay ÇELEBİ
Ömer ŞENTÜRK
Dilek BAYRAMGÜRLER
Ergun VELİDEDEOĞLU
Hülya DAL
Saadettin HÜLAGÜ
Pages
45–47
Publication Date
1997-04-30
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Management of FAPC is surgery

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Familial Adenomatous Polyposis Coli (FAPC) Syndromes are rare dominantly inherited syndromes characterized by hundreds to thousands of colonic adenomatous polyps.
📊
Key Findings & Data:Extraintestinal abnormalities of Gardner syndrome are osteomas, soft tissue tumors, thyroid and adrenal tumors, hypertrophy of the retinal pigment epithelium.
💡
Conclusion & Impact:Management of FAPC is surgery
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Gardner sendromu · Gardner syndrome

Abstract

Familial Adenomatous Polyposis Coli (FAPC) Syndromes are rare dominantly inherited syndromes characterized by hundreds to thousands of colonic adenomatous polyps. Extraintestinal abnormalities of Gardner syndrome are osteomas, soft tissue tumors, thyroid and adrenal tumors, hypertrophy of the retinal pigment epithelium. Management of FAPC is surgery

Özet

Ailesel adenomatöz polipozis koli sendromları; kolonda yüzlerce-binlerce adenomatöz poliple karakterize, nadir görülen, otozomal dominant geçişli sendromlardır. Gardner sendromundaki ekstraintestinal bulgular; osteomalar, yumuşak doku tümörleri, tiroid ve adrenal tümörleri ve retinal pigment epitel hipertrofisidir. Tedavi cerrahidir.

🔖

Cite This Article

ÇELEBİ, A., ŞENTÜRK, Ö., BAYRAMGÜRLER, D., VELİDEDEOĞLU, E., DAL, H., HÜLAGÜ, S. (1997). Gardner Syndrome: Case Report. OPUS Toplum Araştırmaları Dergisi, Cilt: 2 - Sayı: 2, 45–47. https://ajindex.com/articles/856614

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (6)

  1. Burt RW, Bishop DT, Lynch HT, Rozen P, Winawer SJ. Risk and surveillance of individuals with heritable factors for colorectal cancer. WHO Collaborating Centre for the Prevention of Colorectal Cancer. Bull World Health Organ. 1990;68(5):655-665.
  2. Pathak S, Hopwood VL, Hughes JI, Jackson GL. Identification of colon cancer-predisposed individuals: a cytogenetic analysis. Am J Gastroenterol. 1991;86(6):679-684.
  3. Tonelli F, Nardi F, Bechi P, Taddei G, Gozzo P, Romagnoli P. Extracolonic polyps in familial polyposis coli and Gardner's syndrome. Dis Colon Rectum. 1985;28(9):664-668. doi: 10.1007/bf02553447 Nannery WM, Barone JG, Abouchedid C. Familial polyposis coli & Gardner's syndrome. N J Med. 1990;87(9):731-733.
  4. Bridge JA, Sreekantaiah C, Mouron B, Neff JR, Sandberg AA, Wolman SR. Clonal chromosomal abnormalities in desmoid tumors. Implications for histopathogenesis. Cancer. 1992;69(2):430-436. doi:10.1002/1097-0142(19920115)69:2 3.0.co;2-h Salvi G, Menucci R, Scrivanti M, Valanzano R. [Hypertrophy of the pigment epithelium in familial intestinal polyposis]. Ophtalmologie. 1990;4(3):246-248.
  5. Davies DR, Armstrong JG, Thakker N, et al. Severe Gardner syndrome in families with mutations restricted to a specific region of the APC gene. Am J Hum Genet. 1995;57(5):1151-1158.
  6. Bell B, Mazzaferri EL. Familial adenomatous polyposis (Gardner's syndrome) and thyroid carcinoma. A case report and review of the literature. Dig Dis Sci. 1993;38(1):185-190. doi:10.1007/bf01296795 Naylor EW, Gardner EJ. Adrenal adenomas in a patient with Gardner's syndrome. Clin Genet. 1981;20(1):67-73. doi:10.1111/j.1399-0004.1981.tb01810.x Zeze F, Ohsato K, Mitani H, Ohkuma R, Koide O. Hepatocellular carcinoma associated with familial polyposis of the colon. Report of case. Dis Colon Rectum. 1983;26(7):465-468. doi: 10.1007/bf02556528 Danes BS, Deschner EE. Detection of in vitro tetraploidy in heritable colon cancer syndromes. Confirmation by three different assays. Cancer. 1984;54(7):1353-1359. doi:10.1002/1097-0142(19841001)54:7 3.0.co;2-7 Heim S. In vitro growth characteristics of skin fibroblasts from patients with adenomatosis of the colon and rectum and their relatives. Clin Genet. 1983;23(1):41-48. doi:10.1111/j.1399-0004.1983.tb00436.x Sams JS, Lynch HT, Burt RW, Boland CR. Abnormlities in lectin binding profiles in familial colon cancer and familial polyposis coli. Gastroenterology. 1985;88:1568. Heim S, Johansen SG, Kolnig AM, Strömbeck B. Increased levels of spontaneous and mutagen-