SavedAdd your journal

Journals / OPUS Toplum Araştırmaları Dergisi / 1997 / Cilt: 2 - Sayı: 2

Histochemical Characteristics of Early and Late Fetal Period of Human Stomach Mucosa

İnsan Mide Mukozasının Erken ve Geç Fetal Gelişim Surecindeki Histokimyasal Özellikler

Süreyya CEYLAN
Gülay YEGİNOĞLU
Melda YARDIMOĞLU
Sibel KÖKTÜRK
Pages
12–15
Publication Date
1997-04-30
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

CEA as criterion of embryonic proliferation decreases on the fetal maturation.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In this study, histochemical characteristics of mucous glands of the seven fetal gastric antrum are investigated.
📊
Key Findings & Data:The relation between the presence of gastric acid mucosubstances by PAS, AB (pH 2.5), I-/ ID staining techniques and differentiation and maturation is searched.
💡
Conclusion & Impact:CEA as criterion of embryonic proliferation decreases on the fetal maturation.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Fetal Mide Antrumu · Karsinoembryonik Antijen · Periyodik Asid Schiff

Abstract

In this study, histochemical characteristics of mucous glands of the seven fetal gastric antrum are investigated. The relation between the presence of gastric acid mucosubstances by PAS, AB (pH 2.5), I-/ ID staining techniques and differentiation and maturation is searched. PAS, HID and AB (p H 2.5) staining techniques as indicator on the neutral and acid mucopolysaccarides demonstration of gland epithelial are used. CEA is known as proliferation antigen and value of CEA as a research techniques is discussed in the fetal maturation. CEA as criterion of embryonic proliferation decreases on the fetal maturation.

Özet

Bu çalışmada 7 fetal mide antrum biyopsi örneklerinde mide mukoza bezlerinin histoşimik özellikleri araştırıldı. PAS (Perriyodik Asid Schiff), AB (Alcian Blue) pH 2.5 ve HID (Yükseltgenmiş Demir Diamin Aktivitesi) histokimyasal reaksiyonları ile mide mukoza bezlerinde mukosubstansların gelişim sürecindeki diferensiasyon ve matürasyon ile ilişkisi araştırıldı. PAS (pH 7) nötr mukopolisakkaritlerin, HID ve AB (pH 2.5) asit mukopolisakkaritlerin bez epitel hücrelerinde ışık mikroskobunda gösterilebilmesi için kullanıldı. CEA (Carcinoembryonic Antigen) proliferasyon bildiren bir antigen olduğu ve bunun fetal gelişimdeki araştırma tekniği olarak değeri tartışıldı. Embriyonal proliferasyonun bir kriteri olması nedeniyle CEA fetal matürasyon sürecinde azalmaktadır.

🔖

Cite This Article

CEYLAN, S., YEGİNOĞLU, G., YARDIMOĞLU, M., KÖKTÜRK, S. (1997). Histochemical Characteristics of Early and Late Fetal Period of Human Stomach Mucosa. OPUS Toplum Araştırmaları Dergisi, Cilt: 2 - Sayı: 2, 12–15. https://ajindex.com/articles/856593

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (7)

  1. Bloom W, Fawcett DW. A text book of Histology. In: Bloom W, Fawcett DW,eds. A text book of Histology. 11st ed. USA: Saunders Company; 1986:624-640. Cormack DH. Ham’s Histology. In: Cormack DH, ed. Ham’s Histology. 19th ed. USA, New York: Lippincott; 1987:494-501. Lindgren J. Carcinoembryonic antigen in fetal tissues and in material serum. Acta Pathol Microbiol Scand A. 1980;88(1):49-53.
  2. Wagener C, Hain F, Födisch HJ, Breuer H. Localisation of carcinoembryonic antigen in embryonic and fetal human tissues. Histochemistry. 1983;78(1):1-9. doi: 10.1007/bf00491105 von Kleist S, Winkler J, Migule I, Böhm N. Carcinoembryonic antigen (CEA) expression in early embryogenesis: a study of the first trimester of gestation. Anticancer Res. 1986;6(6):1265-1272. Nadji M. Immunoperoxidase Techniques: A Practical Approach to Tumor Diagnosis. In: Nadji M, ed. Immunoperoxidase Techniques: A Practical Approach to Tumor Diagnosis. USA: American Society of Clinical Pathologists; 1986:1-10. Taylor C. Immunoperoxidase techniques: practical and theoretical aspects. Arch Pathol Lab Med. 1978;102:113–131.
  3. Nielsen K, Teglbjaerg PS. On the occurrence of carcinoembryonic antigen (CEA) in different types of intestinal metaplasia of the human stomach. Tumour Biol. 1984;5(6):313-320. Burtin P, von Kleist S, Sabine MC, King M. Immunohistological localization of carcinoembryonic antigen and nonspecific cross-reacting antigen in gastrointestinal normal and tumoral tissues. Cancer Res. 1973;33(12):3299-3305.
  4. Skinner JM, Whitehead R. Tumor markers in carcinoma and premalignant states of the stomach in humans. Eur J Cancer Clin Oncol. 1982;18(3):227-235. doi:10.1016/0277-5379(82)90041-4
  5. Wurster K, Rapp W. Histological and immunohistological studies on gastric mucosa. I. The presence of CEA in dysplastic surface epithelium. Pathol Res Pract. 1979;164(3):270-81. doi: 10.1016/S0344-0338(79)80049-7
  6. Burtin P, Sabine MC, Chavanel G. A comparative study of the localization of CEA and NCA2 in cancerous and normal gastrointestinal tissues. Int J Cancer. 1977;19(5):634-41. doi:10.1002/ijc.2910190507 Fillipe MI, Bogomoletz W, Davson P, Fablan B, Patet F. Intestinal metaplasia subtypes in the assessment of gastric cancer risk. A multicentre prospective study. GUT. 1984;24(10):974-975.
  7. Tsutsumi Y, Onoda N, Misawa M, Kuroki M, Matsuoka Y. Immunohistochemical demonstration of nonspecific cross-reacting antigen in normal and neoplastic human tissues using a monoclonal antibody. Comparison with carcinoembryonic