Etanercept-Induced Thrombocytopenia In A Patient With Ankylosing Spondylitis

Objective & Hypothesis:Tumor necrosis factor-alpha (TNF-α), which is produced by macrophages and activated T lymphocyte cells, plays a main role in inducing further stimulation of other inflammatory cells.

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Key Findings & Data:Anti-TNF-α drugs are used for induction and preservation of remission in patients with Ankylosing spondylitis.

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Conclusion & Impact:We report the case of a 40-year-old man diagnosed with Ankylosing spondylitis who developed Etanercept-induced isolated thrombocytopenia.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Thrombocytopenia · Ankylosing Spondylitis · adverse effect

Abstract

Tumor necrosis factor-alpha (TNF-α), which is produced by macrophages and activated T lymphocyte cells, plays a main role in inducing further stimulation of other inflammatory cells. Anti-TNF-α drugs are used for induction and preservation of remission in patients with Ankylosing spondylitis. Etanercept, which is one of the most used Anti-TNF-α drugs, has side effects such as cytopenia but isolated thrombocytopenia is an uncommon adverse event. We report the case of a 40-year-old man diagnosed with Ankylosing spondylitis who developed Etanercept-induced isolated thrombocytopenia.

Keywords

Thrombocytopenia Ankylosing Spondylitis adverse effect biological agents

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Cite This Article

ÖNMEZ, A., ALTUN, G., AKBAŞ, T., ÖNEÇ, B. (2022). Etanercept-Induced Thrombocytopenia In A Patient With Ankylosing Spondylitis. DAHUDER Medical Journal, Cilt: 2 - Sayı: 1, 28–29. https://ajindex.com/articles/850962

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References (1)

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