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Journals / Ata-Kimya Dergisi / 2022 / Cilt: 2 - Sayı: 1

Paraben Substituted Monospiro-Cyclotriphosphazene Compounds: Synthesis and Characterization

Paraben Sübstitüe Monospiro-Siklotrifosfazen Bileşikleri: Sentezi ve Karakterizasyonu

Nagihan BAYIK TÜLÜCE
Gönül YENİLMEZ ÇİFTÇİ
Pages
6–34
Publication Date
2022-11-11
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The molecular structure of compound 5 was also determined by single crystal X-ray crystallography.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Parabens are among the potential biologically active compounds due to their low toxicity potential for humans and their effective antibacterial and antifungal activity.
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Key Findings & Data:The properties of cyclotriphosphazenes increase their efficiency according to the properties of the side groups to which they are attached.
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Conclusion & Impact:The molecular structure of compound 5 was also determined by single crystal X-ray crystallography.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Siklotrifosfazen · Paraben · NMR

Abstract

Parabens are among the potential biologically active compounds due to their low toxicity potential for humans and their effective antibacterial and antifungal activity. The properties of cyclotriphosphazenes increase their efficiency according to the properties of the side groups to which they are attached. For this reason, scientists use it as a platform to design target molecules in particular. In this study, new types paraben substituted monospiro-cyclotriphosphazene compounds (5-7) were successfully synthesized and these compounds were fully characterized by MALDI-TOF mass, 1H, 31P and 13C spectroscopy techniques. The molecular structure of compound 5 was also determined by single crystal X-ray crystallography.

Özet

Parabenler, insanlar için düşük toksisite potansiyelleri ve etkili antibakteriyel ve antifungal aktiviteleri nedeniyle potansiyel biyolojik olarak aktif bileşikler arasındadır. Siklotrifosfazenlerin özellikleri bağlı oldukları yan grupların özelliklerine göre etkinliklerini arttırır. Siklotrifosfazenlerin göstermiş oldukları özellikler, yan gruplara bağlı olarak değişir ve etkinlikleri artar. Bu nedenle bilim adamları, özellikle hedef molekülleri tasarlamak için bir platform olarak kullanırlar. Bu çalışmada, yeni tip paraben ikameli monospiro-siklotrifosfazen bileşikleri (5-7) başarıyla sentezlendi ve bu bileşikler MALDI-TOF kütlesi, 1H, 31P ve 13C NMR spektroskopi teknikleri ile tamamen karakterize edildi. Bileşik 5'in moleküler yapısı da tek kristal X-ışını kristallografisi ile belirlendi.

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Cite This Article

TÜLÜCE, N. B., ÇİFTÇİ, G. Y. (2022). Paraben Substituted Monospiro-Cyclotriphosphazene Compounds: Synthesis and Characterization. Ata-Kimya Dergisi, Cilt: 2 - Sayı: 1, 6–34. https://ajindex.com/articles/850414

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