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Journals / Türk Jinekolojik Onkoloji Dergisi / 2021 / Cilt: 22 - Sayı: 1

Chronic Kidney Failure in a Patient with Stage IV Epithelial Ovarian Cancer After Cytoreductive Surgery Following HIPEC with Cisplatin: A Case Report

Evre IV Epitelyal Over Kanseri Olan Hastada Sitoredüktif Cerrahi ve Sisplatin ile HİPEK Sonrası Kronik Böbrek Yetmezliği: Olgu Sunumu

Esra BİLİR
Doğan VATANSEVER
Fatih Selçuk BİRİCİK
Tuncay DAĞEL
Şule YILDIZ
Selim MISIRLIOĞLU
Tonguç ARSLAN
Bülent ÇUHACI
Çağatay TAŞKIRAN
Pages
31–34
Publication Date
2021-03-22
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Although a recent study showed that HIPEC following interval CRS improves the overall survival in patients with stage III EOC, its complications are not well studied.

📌 3 Key Takeaways

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Objective & Hypothesis:The mainstay of treatment for advanced-stage ovarian cancer is a maximal surgical effort for complete cytoreduction (CRS) defined as no visible residual disease followed by platinum-based adjuvant chemotherapy.
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Key Findings & Data:This report aims to present a 45-year-old female with advanced-stage EOC who had neoadjuvant chemotherapy, followed by CRS and HIPEC with cisplatin.
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Conclusion & Impact:Although a recent study showed that HIPEC following interval CRS improves the overall survival in patients with stage III EOC, its complications are not well studied.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Yumurtalık kanseri · sitoredüksiyon · HİPEK

Abstract

The mainstay of treatment for advanced-stage ovarian cancer is a maximal surgical effort for complete cytoreduction (CRS) defined as no visible residual disease followed by platinum-based adjuvant chemotherapy. Hyperthermic intraperitoneal chemotherapy (HIPEC) has been started to use for advanced-stage epithelial ovarian cancer (EOC). Although a recent study showed that HIPEC following interval CRS improves the overall survival in patients with stage III EOC, its complications are not well studied. This report aims to present a 45-year-old female with advanced-stage EOC who had neoadjuvant chemotherapy, followed by CRS and HIPEC with cisplatin. Postoperatively, she developed acute kidney injury that was found to be due to HIPEC with cisplatin and complicated by chronic renal failure requiring lifelong hemodialysis.

Özet

İleri evre over kanseri tedavisinde maksimal sitoredüksiyon sonrası platin bazlı kemoterapi yaygın olarak kullanılan standart tedavi yaklaşımıdır. Son yıllarda ileri evre epitelyal over kanseri (EOK) için hipertermik intraperitoneal kemoterapi (HİPEK) uygulanasıda sık kullanılmaya başlanmıştır. Yakın tarihli yapılan bir çalışmada TSR'yi takip eden HİPEK'in evre III EOK'li hastalarda genel sağkalımı artırdığı gösterilmesine rağmen HİPEK komplikasyonları iyi çalışılmamıştır. Bu çalışmada, neoadjuvan kemoterapi ve ardından TSR’yi takiben sisplatin ile HİPEK alan 45 yaşında ileri evre EOK tanılı hastada gelişen postoperatif kronik böbrek yetmezliği sunulmuştur

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Cite This Article

BİLİR, E., VATANSEVER, D., BİRİCİK, F. S., DAĞEL, T., YILDIZ, Ş., MISIRLIOĞLU, S., ARSLAN, T., ÇUHACI, B., TAŞKIRAN, Ç. (2021). Chronic Kidney Failure in a Patient with Stage IV Epithelial Ovarian Cancer After Cytoreductive Surgery Following HIPEC with Cisplatin: A Case Report. Türk Jinekolojik Onkoloji Dergisi, Cilt: 22 - Sayı: 1, 31–34. https://ajindex.com/articles/845156

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References (6)

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