Journals / Türk Jinekolojik Onkoloji Dergisi / 2021 / Cilt: 22 - Sayı: 1

Management of Locally Advanced Cervical Cancer: A Contemporary Review

Lokal İleri Evre Serviks Kanseri Yönetimi: Güncel Derleme

Pages
9–14
Publication Date
2021-03-22
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review article, treatment options in locally advanced cervical cancer will be discussed in chronological order in light of literature.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Cervical cancer is the fourth most frequently diagnosed cancer and the fourth leading cause of cancer death in women.
📊
Key Findings & Data:Treatment strategy is quite certain in early and advanced stages, but there are controversies in the treatment of locally advanced cervical cancers.
💡
Conclusion & Impact:In this review article, treatment options in locally advanced cervical cancer will be discussed in chronological order in light of literature.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Serviks kanseri · lokal ileri evre · cerrahi tedavi

Abstract

Cervical cancer is the fourth most frequently diagnosed cancer and the fourth leading cause of cancer death in women. Treatment strategy is quite certain in early and advanced stages, but there are controversies in the treatment of locally advanced cervical cancers. While clasical literature compares raditherapy and surgical therapy in the management of locally advanced cervical cancer, concominant chemoradiotherapy is considering as a novel therapeutic option. In this review article, treatment options in locally advanced cervical cancer will be discussed in chronological order in light of literature.

Özet

Servikal kanser sıklığı dünyada kadın kanserleri ve kadın kansere bağlı ölümleri arasında dördüncü sıradadır. Erken evre ve ileri evre servikal kanserlerde tedavi yaklaşımı göreceli olarak net olmakla birlikte lokal ileri servikal kanserlerdeki tedavi yaklaşımı tartışmalı bir konudur. Klasik literatür radyoterapi ve cerrahi tedavinin karşılaştırılması şeklinde iken son yıllarda eş zamanlı radyokemoterapi de etkin bir yöntem olarak değerlendirilmektedir. Bu derlemede lokal ileri servikal kanserlerde tedavi yaklaşımları tarihsel olarak değerlendirilecek ve güncel yaklaşımlar literatür eşliğinde özetlenecektir.

🔖

Cite This Article

HASDEMİR, P. S., GÜVENAL, T. (2021). Management of Locally Advanced Cervical Cancer: A Contemporary Review. Türk Jinekolojik Onkoloji Dergisi, Cilt: 22 - Sayı: 1, 9–14. https://ajindex.com/articles/845151

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018 Nov
  2. 68(6):394-424. Erratum in: CA Cancer J Clin. 2020
  3. 313 2- Pecorelli S. Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium. Int J Gynaecol Obstet 2009
  4. 103–4. 3- Bhatla N, Aoki D, Sharma DN, Sankaranarayanan R. Cancer of the cervix uteri. Int J Gynaecol Obstet 2018
  5. 22–36. 4- Falcetta FS, Medeiros LR, Edelweiss MI, Pohlmann PR, Stein AT, Rosa DD. Adjuvant platinum-based chemotherapy for early stage cervical cancer. Cochrane Database Syst Rev. 2016
  6. CD005342. 5- Cibula D, Pötter R, Chiva L, Planchamp F, Avall-Lundqvist E, Raspollini MR. The European Society of Gynaecological Oncology / European Society for Radiotherapy and Oncology /European Society of Pathology Guidelines for the Management of Patients With Cervical Cancer. International Journal of Gynaecological Cancer 2018
  7. Newton M, Hickman B, Bolten A. Radical hysterectomy versus radiotherapy in stage I cervical cancer: preliminary results. Obstet Gynecol. 1964
  8. 563–568. 7- Newton M. Radical hysterectomy or radiotherapy for stage I cervical cancer. Am J Obstet Gynecol. 1975
  9. 535–542. 8- Morley GW, Seski JC. Radical pelvic surgery versus radiation therapy for stage I carcinoma of the cervix (exclusive of microinvasion). Am J Obstet Gynecol. 1976
  10. 785–798. 9- Brewster WR, Monk BJ, Ziogas A, Anton-Culver H, Yamada SD, Berman ML. Intent-to-treat analysis of stage Ib and IIa cervical cancer in the United States: radiotherapy or surgery 1988-1995. Obstet Gynecol. 2001
  11. 97(2):248-254. 10- Bansal N, Herzog TJ, Shaw RE, Burke WM, Deutsch I, Wright JD. Primary therapy for early-stage cervical cancer: radical hysterectomy vs radiation. Am J Obstet Gynecol. 2009
  12. e1-485.e4859. 11- Doll KM, Donnelly E, Helenowski I, Rosenbloom LBS, Small W, Schink JC, Lurain JR. Radical Hysterectomy Compared With Primary Radiation for Treatment of Stage IB1 Cervix Cancer, American Journal of Clinical Oncology. 2014
  13. Landoni F, Maneo A, Colombo A, et al. Randomised study of radical surgery versus radiotherapy for stage Ib-IIa cervical cancer. Lancet. 1997
  14. Landoni F, Colombo A, Milani R, Placa F, Zanagnolo V, Mangioni C. Randomized study between radical surgery and radiotherapy for the treatment of stage IB-IIA cerv