Journals / The Ulutas Medical Journal / 2017 / Cilt: 3 - Sayı: 2

Meta-analysis for Searching Efficacy of Tinidazole and Metronidazole

Pages
32–38
Publication Date
2017-04-01
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therefore the current study was hypothesized that tinidazole is a better option for managing anaerobic, amebic and protozoal infection as compared to metronidazole.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The 5-nitroimidazole antimicrobial agents are considered as the treatment of choice for managing the amebic, protozoal and anerobic infections since 1969.
📊
Key Findings & Data:With the advancement in medical field certain preference of drugs in this group were given.
💡
Conclusion & Impact:Therefore the current study was hypothesized that tinidazole is a better option for managing anaerobic, amebic and protozoal infection as compared to metronidazole.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Tinidazole · Metronidazole · Comparative efficacy

Abstract

The 5-nitroimidazole antimicrobial agents are considered as the treatment of choice for managing the amebic, protozoal and anerobic infections since 1969. With the advancement in medical field certain preference of drugs in this group were given. Tinidazole is now considered as a better one as compared to metronidazole because of specific pharmacokinetic & pharmacodynamics properties. Therefore the current study was hypothesized that tinidazole is a better option for managing anaerobic, amebic and protozoal infection as compared to metronidazole.

🔖

Cite This Article

ZAFAR, H., BUKHARİ, K. T., NOOR, N., HUMAYOUN, S., LAKHNANA, N. K. (2017). Meta-analysis for Searching Efficacy of Tinidazole and Metronidazole. The Ulutas Medical Journal, Cilt: 3 - Sayı: 2, 32–38. https://ajindex.com/articles/844482

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Sim Fung HB, Doan TL, Malar J. Tinidazole: a nitroimida zole antiprotozoal agent.Clin Ther. 2005;27(12):1859-84.
  2. Löfmark S, Edlund C, Nord CE. Metronidazole is still the drug of choice for treatment of anaerobic infections. Clin Infect Dis. 2010;50(1):16–23.
  3. Armstrong NR, Wilson JD. Tinidazole in the treatment of bacterial vaginosis. Int J Womens Health. 2010;1(1):59–65. Armstrong NR,Wilson JD. Tinidazole in the treatment of bacterial vaginosis. Int J Womens Health. 2011; 3(2): 295– 305. Menard JP. Antibacterial treatment of bacterial vaginosis: current and emerging therapies. Int J Womens Health. 2009; 1(1): 59–65.
  4. Raja IM, Basavareddy A, Mukherjee D, Meher BR. Rando- mized, double-blind, comparative study of oral metroni- dazole and tinidazole in treatment of bacterial vaginosis. Indian J Pharmacol 2016;48 (6):654-8.
  5. Macareo L, Lwin KM, Cheah PY, Yuentrakul P, Miller RS, Nosten F etal. Triangular test design to evaluate tinidazole in the prevention of Plasmodium vivax relapse. Malar J. 2013; 12(4): 173. Livengood CH, Ferris DG, Wiesenfeld HC. Effectiveness of two tinidazole regimens in treatment of bacterial vagino- sis: a randomized controlled trial. Obstet Gynecol. 2007; 110 (3):302–309.
  6. Oduyebo OO, Anorlu RI, Ogunsola FT. The effects of antimicrobial therapy on bacterial vaginosis in nonpreg- nant women. Cochrane Database Syst Rev. 2009;3(4): 55-60.
  7. Brandt M, Abels C, May T, Lohmann K, Winkler SI, Hoyme UB etal. Intravaginally applied metronidazole is as effective as orally applied in the treatment of bacterial vaginosis, but exhibits significantly less side effects. Eur J Obstet Gynecol Reprod Biol. 2008;141(5):158–162.
  8. Hanson JM, Gregor MJA, Hillier SL. Metronidazole for bacterial vaginosis. A comparison of vaginal gel vs oral therapy. J Reprod Med. 2000;45(2):889–896.
  9. Buranawarodomkul P, Chandeying V, Sutthijumroon S. Seven day metronidazole versus single dose tinidazole as therapy for nonspecific vaginitis. J Med Assoc Thai. 1990;73(1):283–7.
  10. Sanz SF, Hernanz A, Sancher E. Comparative trial of metronidazole versus tinidazole in the treatment of non specific vaginitis. Rev Esp Obst y Gin. 1985;44(1):717–20.
  11. Thulkar J, Kriplani A, Agarwal N. A comparative study of oral single dose of metronidazole, tinidazole, secnidazole and ornidazole in bacterial vaginosis. Indian J Pharmacol 2012;44(2):243-5
  12. Bakshi JS, Ghiara, JM, Nanivadekar AS. How Does Tinidazole Compare with Metronidazole? Drugs.1978; 15(1): 33–42
  13. Bhalla P, Chawla R, Garg S, Singh MM, Raina