Journals / Klinik Tıp Pediatri Dergisi / 2018 / Cilt: 10 - Sayı: 2

Current Approach to the Diagnosis and Management of Anaphylaxis in Children

Çocuklarda Anafilaksi’nin Tanı ve Tedavisine Güncel Yaklaşım

Pages
18–26
Publication Date
2018-03-06
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Patients and/or parents should be instructed for trigger avoidance/prevention before discharge, emergency preparedness should be completed and allergists shouldbe consulted for long-term follow-up.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Abstract Anaphylaxis is a serious allergic reaction that is rapid in onset and maycause death.
📊
Key Findings & Data:Its prevelance has increased dramatically throughout the world over thelast two decades.
💡
Conclusion & Impact:Patients and/or parents should be instructed for trigger avoidance/prevention before discharge, emergency preparedness should be completed and allergists shouldbe consulted for long-term follow-up.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:anafilaksi · adrenalin · çocuk

Abstract

Abstract Anaphylaxis is a serious allergic reaction that is rapid in onset and maycause death. Its prevelance has increased dramatically throughout the world over thelast two decades. Although anaphylaxis is a clinical diagnosis, there are no specificsigns or symptoms that are diagnostic for anaphylaxis. Further, there is no gold standard laboratory test that can confirm the diagnosis in the acute phase and can be usedin routine practice. Although improved clinical diagnostic criteria have contributed significantly to the resolution of diagnostic problems, diagnosis of many cases canstill be missed in clinical practice. Anaphylaxis is a medical emergency and the only lifesaving treatment is adrenaline. The most important cause of anaphylaxis related death is no or delayed administration of adrenaline. Adrenaline should be administered without any loss of time in any patient who meets the diagnostic criteria for anaphylaxis. Antihistamines and corticosteroids should never be used instead of adrenaline. Every patient should have a certain follow-up time. Patients and/or parents should be instructed for trigger avoidance/prevention before discharge, emergency preparedness should be completed and allergists shouldbe consulted for long-term follow-up.

Özet

ÖzAnafilaksi, yaşamı tehdit eden ve ölümle sonuçlanabilen ani başlangıçlı sistemik aşırı duyarlılık reaksiyonudur. Anafilaksi sıklığı son yirmi yılda tüm dünya genelinde önemli oranda artmıştır. Anafilaksi klinik bir tanı olmasına rağmen ortaya çıkanhiçbir belirti ve bulgu anafilaksiye özgün değildir. Aynı zamanda akut dönemde tanıyı doğrulayabilecek ve rutin pratikte kullanılabilecek altın standart bir laboratuvar testte yoktur. Geliştirilmiş klinik tanı kriterleri tanısal sorunların çözümüne önemli oranda katkıda bulunmuş olsa da halen klinik pratikte birçok olgunun tanısı atlanabilmektedir. Anafilaksi tedavisi acil bir durumdur ve tek hayat kurtarıcı tedavi adrenalindir. Anafilaksiye bağlı ölümler için bilinen en önemli neden adrenalinin uygulanmaması ya da geç uygulanmasıdır. Bu nedenle anafilaksi tanı kriterlerini karşılayan her hastada adrenalin vakit kaybedilmeden uygulanmalıdır. Antihistaminler ve kortikosteroidler hiçbir zaman adrenalin yerine kullanılmamalıdır. Mutlaka her hastanın bir izlem süresi olmalıdır. Taburcu edilmeden önce hasta ve/veya ebeveynlere tetikleyicilerden kaçınma/korunma yöntemleri anlatılmalı, acil durum hazırlığı tamamlanmalı ve uzun süreli izlem için allerji kliniklerine konsülte edilmelidir.

🔖

Cite This Article

ARGA, D. D. M. (2018). Current Approach to the Diagnosis and Management of Anaphylaxis in Children. Klinik Tıp Pediatri Dergisi, Cilt: 10 - Sayı: 2, 18–26. https://ajindex.com/articles/838377

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (1)

  1. Kaynaklar 1.Orhan F, Civelek E, Sahiner UM, Arga M, et al. Anaphyla-xis: Turkish National Guideline 2018. Asthma Allergy Immu-nol 2018; 16 (Suppl 1):1-62. 2.Lieberman P, Nicklas RA, Randolph C, Oppenheimer J, et al.Anaphylaxis--a practice parameter update 2015. Ann AllergyAsthma Immunol. 2015 Nov;115(5):341-84. 3.Simons FE, Ardusso LR, Dimov V, Ebisawa M, et al; WorldAllergy Organization. World Allergy Organization Anaphy-laxis Guidelines: 2013 update of the evidence base. Int ArchAllergy Immunol. 2013;162(3):193-204. 4.Muraro A, Roberts G, Worm M, Bilò MB, et al; EAACI FoodAllergy and Anaphylaxis Guidelines Group. Anaphylaxis: gui-delines from the European Academy of Allergy and ClinicalImmunology. Allergy. 2014 Aug;69(8):1026-45. 5.Simons FE. Anaphylaxis. J Allergy Clin Immunol. 2010;125(2Suppl 2):S161-81. 6.Simons FER. Anaphylaxis. In: Leung DYM, Szefler SJ, Bonil-la FA, Akdis CA, Sampson HA (eds). Pediatric Allergy Prin-ciples and Practice. 3rd edition. Philadelphia: Saunders Els-evier, 2016:371-76. 7.Brown GA, Kemp SF, Lieberman PL. Anapyhylaxis. In: Ad-kinson NF Jr, Bochner BS, editors. Middleton’s Allergy: principles and practice. 8th ed. Philadelphia: Saunders, Inc; 2014;1237-60. 8.Lieberman P, Camargo CA Jr, Bohlke K, et al. Epidemiologyof anaphylaxis: findings of the American College of Allergy, Asth-ma and Immunology Epidemiology of Anaphylaxis Working Gro-up. Ann Allergy Asthma Immunol. 2006;97(5):596-602. 9.Liew WK, Williamson E, Tang ML. Anaphylaxis fatalities andadmissions in Australia. J Allergy Clin Immunol.2009;123(2):434-42. 10.Panesar SS, Javad S, de Silva D, Nwaru BI, et al; EAACI FoodAllergy and Anaphylaxis Group. The epidemiology of anaphy-laxis in Europe: a systematic review. Allergy. 2013Nov;68(11):1353-61. 11.Pumphrey RS, Roberts IS. Postmortem findings after fatalanaphylactic reactions. J Clin Pathol. 2000;53(4):273-6. 12.Simons FE. Anaphylaxis in infants: can recognition and ma-nagement be improved? J Allergy Clin Immunol.2007;120(3):537-40. 13.Sampson HA, Muñoz-Furlong A, Campbell RL, Adkinson NFJr, Bock SA, Branum A, et al. Second symposium on the de-finition and management of anaphylaxis: summary report--Second National Institute of Allergy and InfectiousDisease/Food Allergy and Anaphylaxis Network symposium.J Allergy Clin Immunol. 2006;117(2):391-7 14.Demoly P, Adkinson NF, Brockow K, Castells M, Chiriac AM,Greenberger PA, et al. International Consensus on drug al-lergy. Allergy 2014;69:420-37. 15.Mirakian R, Ewan PW, Durham