SavedAdd your journal

Journals / International Journal of Food Engineering Research / 2017 / Cilt: 3 - Sayı: 2

AKKERMANSIA MUCINIPHILA; ,FUNCTIONAL AND PROBIOTIC PROPERTIES IN THE GASTROINTESTINAL TRACT

Murat DOĞAN
Merve ÖZTAĞ
Hilal DEMİRKESEN BIÇAK
Pages
29–35
Publication Date
2017-10-01
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It was found recently that one of the intestinal bacteria isolated from human fecal samples, Akkermansia muciniphila, meets the need for nutrition of itself and other bacteria by grafting to the mucus layer and providing the monomer by degrading mucin which is the main component of mucus.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The development of microbial communities in the human gastrointestinal tract begins immediately after birth.
📊
Key Findings & Data:Akkermansia muciniphila, which has positive effects on human gut microbiota, decreases in microbiota in the presence of certain chronic diseases.
💡
Conclusion & Impact:It was found recently that one of the intestinal bacteria isolated from human fecal samples, Akkermansia muciniphila, meets the need for nutrition of itself and other bacteria by grafting to the mucus layer and providing the monomer by degrading mucin which is the main component of mucus.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Akkermansia muciniphila · gut microbiota · probiotic properties

Abstract

The development of microbial communities in the human gastrointestinal tract begins immediately after birth. Human gut microbiota is comprised of the millions of bacterial microbial communities that are effective in protecting the health of the host organism and share the common site with the host. At the same time, the mucus layer formed by the epithelial cells surrounding the intestinal surface protects intestines against intestinal external factors and meets the microbiota’s need for nutrition. It was found recently that one of the intestinal bacteria isolated from human fecal samples, Akkermansia muciniphila, meets the need for nutrition of itself and other bacteria by grafting to the mucus layer and providing the monomer by degrading mucin which is the main component of mucus. Akkermansia muciniphila, which has positive effects on human gut microbiota, decreases in microbiota in the presence of certain chronic diseases. Recent studies have shown that decreasing amounts of Akkermansia muciniphila was also found in the feces samples of individuals with chronic diseases such as obesity and diabetes, and as well as found in the gastrointestinal tract, too.

🔖

Cite This Article

DOĞAN, M., ÖZTAĞ, M., BIÇAK, H. D. (2017). AKKERMANSIA MUCINIPHILA; ,FUNCTIONAL AND PROBIOTIC PROPERTIES IN THE GASTROINTESTINAL TRACT. International Journal of Food Engineering Research, Cilt: 3 - Sayı: 2, 29–35. https://ajindex.com/articles/832965

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Sanders, M. E. “Impact of probiotics on colonizing microbiota of the gut,” Journal of clinical Gastroenterology, vol. 45, pp.115-119, 2011
  2. Derrien M, van Baarlen P, Hooiveld G, Norin E, Muller M, de Vos WM. “Modulation of mucosal immune response, tolerance and proliferation in mice colonized by the mucin-degrader Akkermansia muciniphila,” Frontiers in cellular and Infection Microbiology, vol. 2, pp.166, 2011
  3. Reid G, Younes JA, Van der Mei Hc, Gloor GB, Knight R, Busscher HJ. “Microbiota restoration: natural and supplemented recovery of human microbial communities,” Nature Reviews Microbiology, vol. 9, pp.27–38, 2011
  4. Derrien, M., Belzer, c., & de Vos, W. M. “Akkermansia muciniphila and its role in regulating host functions,” Microbial pathogenesis, vol. 106, pp.171-181, 2017
  5. Derrien, M., Vaughan, E. E., Plugge, c. M., & de Vos, W. M. “Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium,” International Journal Of Systematic And Evolutionary Microbiology, vol.54, pp.1469- 1476, 2004 [6] Belzer, c., & De Vos, W. M. “Microbes inside—from diversity to function: the case of Akkermansia,” The ISME Journal, vol. 6, pp.1449, 2012
  6. Hemarajata, P., & Versalovic, J. “Effects of probiotics on gut microbiota: mechanisms of intestinal immunomodulation and neuromodulation,” Therapeutic Advances in Gastroenterology, vol. 6, pp.39-51, 2013
  7. Sekirov, I., Russell, S. L., Antunes, L. c. M., & Finlay, B. B. “Gut microbiota in health and disease,” Physiological Reviews, vol. 90, pp.859- 904, 2010 [9] Mändar, R., & Mikelsaar, M. “Transmission of mother’s microflora to the newborn at birth,” Neonatology, 69(1), 30-35, 1996
  8. O’Hara, A. M., & Shanahan, F. “The gut flora as a forgotten organ,” EMBO reports, vol. 7, pp.688-693, 2006
  9. Vajro, P., Paolella, G., & Fasano, A. “Microbiota and gut-liver axis: a mini-review on their influences on obesity and obesity related liver disease,” Journal of Pediatric Gastroenterology and Nutrition, vol. 56(5), pp.461, 2013 [12] Jandhyala, S. M., Talukdar, R., Subramanyam, c., Vuyyuru, H., Sasikala, M., & Reddy, D. N. “Role of the normal gut microbiota,” World Journal of Gastroenterology: WJG, vol. 21(29), pp.8787, 2015
  10. Shen, J. “Mechanism of Triglyceride Lowering Action of Akkermansia muciniphila and Fenugreek in a Genetic Induced Hyperlipidemia,” 2016
  11. Everard, A., Belzer, c., Geurts, L., Ouwerkerk, J. P., Druart, c., Bindels, L. B.,. & De Vos, W. M. “cross