Journals / Anatolian Journal of Biology / 2021 / Cilt: 2 - Sayı: 1

Evaluation of Glycyrrhiza Species as Medicinal Plant

Pages
1–11
Publication Date
2021-06-30
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

To find their new bioactive compounds against different diseases, studies on Glycyrrhiza species should be increased.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In this study, Glycyrrhiza species cultivated in Turkey assessed in terms of their chemical composition, morphological features and therapeutic activities.
📊
Key Findings & Data:Potassium and calcium salts including licritic acid, gylcertatol and glycyrrhic acid have been found in the roots.
💡
Conclusion & Impact:To find their new bioactive compounds against different diseases, studies on Glycyrrhiza species should be increased.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Glycyrrhiza · Therapeutic Agent · Phenolic Compounds

Abstract

In this study, Glycyrrhiza species cultivated in Turkey assessed in terms of their chemical composition, morphological features and therapeutic activities. Potassium and calcium salts including licritic acid, gylcertatol and glycyrrhic acid have been found in the roots. Glycyrrhizin, a cough suppressor and natural antioxidant, has been determined as major triterpenoid saponin found in roots. Studies revealed that leaves contain flavonoids which have antioxidant and anti-inflammatory effect. Glycyrrhiza species have economic value due to their compounds with different bioactivities such as antioxidant, anti-inflammatory, antimicrobial activity. In recent studies, besides of known therapeutic effects of active compounds obtained from Glycyrrhiza species, it has been investigating whether they have a neuroprotective effect for Alzheimer's disease therapy. In the light of the data in the literature, it has also been revealed side effects of active compounds in this plant species. On the other hand, the side effects of active compounds isolated from these species have been manifested with various data. To find their new bioactive compounds against different diseases, studies on Glycyrrhiza species should be increased.

🔖

Cite This Article

ÇOLAK, F., GENİŞEL, M., URAS, İ. S. (2021). Evaluation of Glycyrrhiza Species as Medicinal Plant. Anatolian Journal of Biology, Cilt: 2 - Sayı: 1, 1–11. https://ajindex.com/articles/824767

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (17)

  1. Armanini, D., et al., History of the endocrine effects of licorice. Experimental and clinical endocrinology & diabetes, 2002. 110(06): p. 257-261
  2. KARAMAN, Ö. and G. ELGİN CEBE, Diyabet ve Türkiye’de antidiyabetik olarak kullanılan bitkiler. 2004. [3] inflata Bat, G. and G. uralensis Fisch, Meyan
  3. Fiore, C., et al., A history of the therapeutic use of liquorice in Europe. Journal of ethnopharmacology, 2005. 99(3): p. 317-324
  4. Jatav, V.S., et al., Recent pharmacological trends of Glycyrrhiza glabra Linn. Unani Res, 2011. 1: p. 1-11
  5. Mayhoff, C., C. Plini Secundi Naturalis historiae libri XXXVII: Libri XXXI-XXXVII. Vol. 5. 1897: In aedibus BG Teubneri
  6. Hort, A., Enquiry into plants and minor works on odours and weather signs, with an English translation by Sir Arthur Hort, bart. 1916
  7. Asl, M.N. and H. Hosseinzadeh, Review of pharmacological effects of Glycyrrhiza sp. and its bioactive compounds. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 2008. 22(6): p. 709-724
  8. Gürhan, G. and E. Nurten, Halk arasında hemoroit tedavisinde kullanılan bitkiler-I. Hacettepe Üniversitesi Eczacılık Fakültesi Dergisi, 2004(1): p. 37-60
  9. AYANOĞLU, F., A. MERT, and D.A. KAYA, Hatay yöresinde halk arasinda kullanilan bazi önemli tibbi ve kokulu bitkilerin tespiti ve toplanmasi. DERGİSİ, 1999: p. 101
  10. EMA. Liquiritiae radix. 2007; Available from:
  11. ESCOP. Table of herb-drug interactions based on the monographs of ESCOP. 2003; Available from:
  12. TITCK. Tıbbi Bitki Monografları. 2020; Available from:
  13. Lakshmi, T. and R. Geetha, Glycyrrhiza glabra Linn. commonly known as licorice: a therapeutic review. Int J Pharm Pharm Sci, 2011. 3(4): p. 20-5
  14. Hayashi, H. and H. Sudo, Economic importance of licorice. Plant Biotechnology, 2009. 26(1): p. 101-104
  15. Bradley, P., British herbal compendium. Volume 2: a handbook of scientific information of widely used plant drugs. 2006: British Herbal Medicine Association
  16. Yamamura, Y., et al., Pharmacokinetic profile of glycyrrhizin in healthy volunteers by a new high‐performance liquid chromatographic method. Journal of pharmaceutical sciences, 1992. 81(10): p. 1042-1046
  17. Tamir, S., et al., Estrogen-like activity of glabrene and other consti