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Journals / SDÜ Tıp Fakültesi Dergisi / 2012 / Cilt: 19 - Sayı: 2

Successful use of vincristine in the management of Kasabach-Merritt Phenomenon

M Asim AYDIN
Ayca KUYBULU
Aslihan BOYACI
Tugba KOCA
Pages
55–58
Publication Date
2012-06-30
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Vincristin therapy may be suggested instead of multidrugs as first line therapy in patients with KMP.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A 2-month old boy with Kaposiform Hemangioendothelioma of the lumbosacral region invading the retroperitoneum was admitted with Kasabach-Merritt Phenomenon.
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Key Findings & Data:After corticosteroid and interferon treatments failed with progression of the disease to a life threatening condition, vincristine monotreatment granted a rapid rise in platelet counts, fibrinogen levels and a resolution in the enlargement of the lesion.
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Conclusion & Impact:Vincristin therapy may be suggested instead of multidrugs as first line therapy in patients with KMP.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Kasabach Merrit Fenomeni · Vincristin

Özet

A 2-month old boy with Kaposiform Hemangioendothelioma of the lumbosacral region invading the retroperitoneum was admitted with Kasabach-Merritt Phenomenon. After corticosteroid and interferon treatments failed with progression of the disease to a life threatening condition, vincristine monotreatment granted a rapid rise in platelet counts, fibrinogen levels and a resolution in the enlargement of the lesion. The remission was maintained and no adverse effects were observed during the treatment. Vincristin therapy may be suggested instead of multidrugs as first line therapy in patients with KMP.

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Cite This Article

AYDIN, M. A., KUYBULU, A., BOYACI, A., KOCA, T. (2012). Successful use of vincristine in the management of Kasabach-Merritt Phenomenon. SDÜ Tıp Fakültesi Dergisi, Cilt: 19 - Sayı: 2, 55–58. https://ajindex.com/articles/799667

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References (11)

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