Journals / SDÜ Tıp Fakültesi Dergisi / 2019 / Cilt: 26 - Sayı: 4

Evaluation of Incomplete Fractures in Contralateral Femurs of Patients with Atypical Femoral Fractures

Atipik Femur Kırığı Olan Hastaların Karşı Femurda İnkomplet Kırık Varlığının Değerlendirilmesi

Pages
458–463
Publication Date
2019-12-01
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

We believe that early detection and treatment with evaluating the risk for impending complete fracture of incomplete atypical femur fractures would prevent the serious morbidity of patients.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Our aim was to investigate the presence of incomplete atypical femur fractures in contralateral femurs of patients who underwent surgical treatment for a complete atypical femur fracture and to compare patients with incomplete fractures and patients without incomplete fractures.
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Key Findings & Data:Material and Methods: The patients who underwent surgical treatment for atypical femur fracture in our clinic between January 2012 and December 2018 were evaluated retrospectively and it was observed that 46 patients fulfilled the inclusion criteria.
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Conclusion & Impact:We believe that early detection and treatment with evaluating the risk for impending complete fracture of incomplete atypical femur fractures would prevent the serious morbidity of patients.
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:atipik femur kırığı · bifosfonat · inkomplet

Abstract

Objective: Our aim was to investigate the presence of incomplete atypical femur fractures in contralateral femurs of patients who underwent surgical treatment for a complete atypical femur fracture and to compare patients with incomplete fractures and patients without incomplete fractures. Material and Methods: The patients who underwent surgical treatment for atypical femur fracture in our clinic between January 2012 and December 2018 were evaluated retrospectively and it was observed that 46 patients fulfilled the inclusion criteria. In all patients, the contralateral femurs were evaluated for an incomplete atypical femur fracture during hospitalization. The patients were divided into two groups according to the presence of incomplete atypical fracture in the contralateral side and age, gender, bisphosphonate usage duration, body mass index values, hip and lumbar T scores, serum parathormone, 25-OH Vitamin D and alkaline phosphatase levels were compared. Results: All patients were women with a mean age 72.9 ± 5.9 years. The mean duration of bisphosphonates was 7.9 ± 1.6 years. In 11 (23.9%) patients, incomplete atypical fracture was detected in contralateral femur. Age, bisphosphonate usage duration, body mass index values, hip and lumbar T scores, serum parathormone, 25-OH Vitamin D and alkaline phosphatase levels were not significantly different between the two groups. Conclusion: We conclude that contralateral femurs of all patients with atypical femur fractures should be evaluated for the evidence of an incomplete fracture. We believe that early detection and treatment with evaluating the risk for impending complete fracture of incomplete atypical femur fractures would prevent the serious morbidity of patients.

Özet

Amaç: Amacımız komplet atipik femur kırığı nedeniyle cerrahi tedavi uygulanan hastaların karşı femurlarını değerlendirerek inkomplet atipik femur kırığı varlığını araştırmak ve inkomplet kırık saptanan hastalar ile inkomplet kırık gözlenmeyen hastaları karşılaştırmaktır. Gereç ve Yöntemler: Kliniğimizde Ocak 2012 ile Aralık 2018 tarihleri arasında atipik femur kırığı nedeniyle cerrahi tedavi uygulanan hastalar retrospektif olarak incelendi ve 46 hastanın çalışmaya dahil edilme kriterlerine uyduğu görüldü. Tüm hastaların yatışları sırasında karşı femurları inkomplet atipik femur kırığı bakımından değerlendirilmişti. Hastalar karşı femurda inkomplet atipik kırık varlığına göre iki gruba ayrıldı ve iki grubun yaşları, cinsiyetleri, bifosfonat kullanım süreleri, vücut kitle indeks değerleri, kalça ve lomber T skorları, serum parathormon, 25-OH Vitamin D ve alkalen fosfataz düzeyleri karşılaştırıldı. Bulgular: Çalışmada yer alan hastaların hepsi kadındı ve hastaların yaş ortalaması 72,9 ± 5,9 yıl olarak bulundu. Hastaların ortalama bifosfonat kullanım süresi 7,9 ± 1,6 yıl olduğu görüldü. 11 (%23,9) hastada karşı femurda inkomplet atipik kırık ile karşılaşıldı. İki grubun yaşları, bifosfonat kullanım süreleri, vücut kitle indeks değerleri, kalça ve lomber T skorları, serum parathormon, 25-OH Vitamin D ve alkalen fosfataz değerleri arasında anlamlı fark saptanmadı. Sonuç: Atipik femur kırığı olan tüm hastaların karşı femurlarının inkomplet kırık varlığı açısından değerlendirilmesi gerektiği kanaatindeyiz. İnkomplet atipik femur kırıklarının erken fark edilmesinin ve komplet kırığa dönüşme riskinin değerlendirerek uygun tedavinin gerçekleştirilmesinin hastalarda oluşabilecek ciddi morbiditeyi engelleyeceğini düşünüyoruz.

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Cite This Article

AKGÜN, U., CANBEK, U. (2019). Evaluation of Incomplete Fractures in Contralateral Femurs of Patients with Atypical Femoral Fractures. SDÜ Tıp Fakültesi Dergisi, Cilt: 26 - Sayı: 4, 458–463. https://ajindex.com/articles/799492

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References (13)

  1. Fischer S, Kapinos KA, Mulcahy A, Pinto L, Hayden O, Barron R. Estimating the long-term functional burden of osteoporosis-related fractures. Osteoporos Int. 2017
  2. 28(10):2843-51. doi:10.1007/s00198-017-4110-4 2. Eroğlu K, Karaöz S, Akkuzu G. Osteoporoz İçin Risk Faktörleri ve Önlenmesi. SDÜ Tıp Fakültesi Dergisi. 1997
  3. 4(2):23-7. 3. Pazianas M, Abrahamsen B. Safety of bisphosphonates. Bone. 2011
  4. 49(1):103-10. doi:10.1016/j.bone.2011.01.003 4. Patel RN, Ashraf A, Sundaram M. Atypical Fractures Following Bisphosphonate Therapy. Semin Musculoskelet Radiol. 2016
  5. 20(4):376-81. doi:10.1055/s-0036-1593766 5. Starr J, Tay YKD, Shane E. Current Understanding of Epidemiology, Pathophysiology, and Management of Atypical Femur Fractures. Curr Osteoporos Rep. 2018
  6. 16(4):519-29. doi:10.1007/s11914-018-0464-6 6. Shane E, Burr D, Abrahamsen B, Adler RA, Brown TD, Cheung AM, et al. Atypical subtrochanteric and diaphyseal femoral fractures: second report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2014
  7. 29(1):1-23. doi:10.1002/jbmr.1998 7. Dell RM, Adams AL, Greene DF, Funahashi TT, Silverman SL, Eisemon EO, et al. Incidence of atypical nontraumatic diaphyseal fractures of the femur. J Bone Miner Res. 2012
  8. 27(12):2544-50. doi:10.1002/jbmr.1719 8. Schilcher J, Michaelsson K, Aspenberg P. Bisphosphonate use and atypical fractures of the femoral shaft. N Engl J Med. 2011
  9. 364(18):1728-37. doi:10.1056/NEJMoa1010650 9. Min BW, Koo KH, Park YS, Oh CW, Lim SJ, Kim JW, et al. Scoring System for Identifying Impending Complete Fractures in Incomplete Atypical Femoral Fractures. J Clin Endocrinol Metab. 2017
  10. 102(2):545-50. doi:10.1210/jc.2016-2787 10. Dell R, Greene D. A proposal for an atypical femur fracture treatment and prevention clinical practice guideline. Osteoporos Int. 2018
  11. 29(6):1277-83. doi:10.1007/s00198-018-4506-9 11. Beaudouin-Bazire C, Dalmas N, Bourgeois J, Babinet A, Anract P, Chantelot C, et al. Real frequency of ordinary and atypical sub-trochanteric and diaphyseal fractures in France based on X-rays and medical file analysis. Joint Bone Spine. 2013
  12. 80(2):201-5. doi:10.1016/j.jbspin.2012.07.012 12. Girgis CM, Sher D, Seibel MJ. Atypical femoral fractures and bisphosphonate use. N Engl J Med. 2010
  13. 362(19):1848-9. doi:10.1056/NEJMc0910389 13. Lim SJ, Yeo I, Yoon PW, Yoo JJ, Rhyu KH, Han SB, et al. Incidence, risk factors, and fracture healing of atypical femoral fractures: a multicenter case-control study. Osteoporos Int. 2