SavedAdd your journal

Journals / Mehmet Akif Ersoy Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi / 2019 / Cilt: 7 - Sayı: 1

Antioxidant effects of curcumin on the blood tissue in rats

Şevkinaz KONAK
Emine Hilal ŞENER
Pages
8–14
Publication Date
2019-06-30
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results of the study show that curcumin strengthens the antioxidant defense system.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Curcumin is a pigment found in Indian saffron spices, also known as turmeric.
📊
Key Findings & Data:In the study, 24 Wistar rats were 8 weeks old, randomly divided into 2 groups which were the control group and the experimental group was fed with curcumin supplement.
💡
Conclusion & Impact:Results of the study show that curcumin strengthens the antioxidant defense system.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Curcumin · blood tissue

Abstract

Curcumin is a pigment found in Indian saffron spices, also known as turmeric. The aim of this study is to investigate the antioxidant effect of curcumin, a phytochemical, on the blood tissue of rats. In the study, 24 Wistar rats were 8 weeks old, randomly divided into 2 groups which were the control group and the experimental group was fed with curcumin supplement. Curcumin supplemented group was fed at 300mg/kg/day curcumin dissolved in corn oil by oral gavage for 12 days. 24 hours after the last feeding, TAC (Total Antioxidant Capacity) and TOC (Total Oxidant Capacity) were analyzed in blood samples. In curcumin supplemented group TAC decreased significantly than control group (p<0,05). When the TOC is examined, in curcumin supplemented group TOC was evaluated statistically higher than in the control group (p<0,05). Results of the study show that curcumin strengthens the antioxidant defense system.

🔖

Cite This Article

KONAK, Ş., ŞENER, E. H. (2019). Antioxidant effects of curcumin on the blood tissue in rats. Mehmet Akif Ersoy Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, Cilt: 7 - Sayı: 1, 8–14. https://ajindex.com/articles/790466

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (4)

  1. Aggarwal, B.B., 2010. Targeting Inflammation-Induced Obesity and Metabolic Diseases by Curcumin and Other Nutraceuticals, Annu Rev Nutr., 21;30:173-99.Aggarwal, B.B., 2010. Targeting Inflammation-Induced Obesity and Metabolic Diseases by Curcumin and Other Nutraceuticals, Annu Rev Nutr. 21;30:173-99.Aggarwal, B.B., 2013. Curcumin-free tumeric exhibits anti-inflammatory and anticancer activities: Identification of novel components of tumeric. Mol Nutr Food Res;57,1529-42.
  2. Aggarwal, BB., Kumar, A., Bharti, AC., 2003. Anticancer Potential of Curcumin: Preclinical and Clinical Studies. Anticancer Research; 23: 363-398.Aggarwal, BB., Sundaram, C., Malani, N., Ichikawa, H., 2007. Curcumin: The Indian solid gold. Adv Exp Med Biol; 595,1–75.Ak, T. and Gulcin, I., 2008. Antioxidant and radical scavenging properties of curcumin Chemico-Biological Interactions.;174, 27–37.
  3. Ammon, H. P. T., Anazoda, M. I., Safayhi, H., Dhawan, B. N. and Srimal R. C., 1992. Curcumin: A potent inhibitor of Leukotriene B4 formation in rat peritoneal polymorphonuclear neutrophils (PMNL), Planta Medica. 58, 26-28.Anand, P., Kunnumakkara, AB., Newman, RA., Aggarwal, BB. 2007. Bioavailability of curcumin: problems and promises. Molecular pharmaceutics 4: 807-818.Änderung L. Curcuma – Sechs Tipps zur richtigen Anwendung. (https://www.z entrum-der-gesundheit.de/curcuma-anwendung-ia.html). Accsess Date: 13.05.2018.Araújo, CC., Leon, LL., 2001. Biological activities of Curcuma longa L. Mem Inst Oswaldo Cruz; 96(5):723-8.Aslan, R., Kutlu, R., Civi, S., Tasyurek, E., 2014. The correlation of the total antioxidant status (TAC), total oxidant status (TOC) and paraoxonase activity (PON1) with smoking. Clin Biochem; 47(6): 393-397.
  4. Auddy, B., Ferreira, M., Blasina, F., Lafon, L., Arredondo, F., Dajas, F., Tripathi, P.C., Seal, T. and Murkerjee, B., 2003. Screening of antioxidant activity of three Indian medicinal plants, traditionally used for the management of neurodegenerative diseases, Journal of Ethnopharmacology, 84, 131-138.Belviranlı, M., Okudan, N., Atalık, KEN., 2012. Effects of curcumin supplementation on oxidant/antioxidant status of heart tissue in aged rats, Genel Tıp Derg; 22(2):61-66.Delgado-Vargas, F., and Paredes-López, O., (Eds): 2003. Natural colorants for food and nutraceutical uses. CRC Press.Duan, W., Yang, Y., Yan, J., Yu, S., Liu, J., Zhou, J., et al,. 2012. The effects of curcumin post-treatment against myocardial ischemia and reperfusion by activation of the JAK2/STAT3 sign